Interpreting Rectal MRI Post-Neoadjuvant Therapy

Joao Miranda; Pamela Causa Andrieu; Josip Nincevic; Lucas de Padua Gomes de farias; Hala Khasawneh; Yuki Arita; Nir Stanietzky; Maria Clara Fernandes; Tiago Biachi De Castria; Natally Horvat

doi:10.20944/preprints202311.0651.v1

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preprints.org > medicine and pharmacology > gastroenterology and hepatology > doi: 10.20944/preprints202311.0651.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Interpreting Rectal MRI Post-Neoadjuvant Therapy

Joao Miranda

^* ,

Pamela Causa Andrieu

Josip Nincevic

Lucas de Padua Gomes de farias

Hala Khasawneh

Yuki Arita

Nir Stanietzky

Maria Clara Fernandes

Tiago Biachi De Castria

Natally Horvat

Version 1 : Received: 8 November 2023 / Approved: 9 November 2023 / Online: 9 November 2023 (14:38:20 CET)

A peer-reviewed article of this Preprint also exists.

Miranda, J.; Causa Andrieu, P.; Nincevic, J.; Gomes de Farias, L.P.; Khasawneh, H.; Arita, Y.; Stanietzky, N.; Fernandes, M.C.; De Castria, T.B.; Horvat, N. Advances in MRI-Based Assessment of Rectal Cancer Post-Neoadjuvant Therapy: A Comprehensive Review. J. Clin. Med. 2024, 13, 172. Miranda, J.; Causa Andrieu, P.; Nincevic, J.; Gomes de Farias, L.P.; Khasawneh, H.; Arita, Y.; Stanietzky, N.; Fernandes, M.C.; De Castria, T.B.; Horvat, N. Advances in MRI-Based Assessment of Rectal Cancer Post-Neoadjuvant Therapy: A Comprehensive Review. J. Clin. Med. 2024, 13, 172.

Abstract

Rectal cancer presents significant diagnostic and therapeutic challenges, with neoadjuvant therapy playing a pivotal role in improving resectability and patient outcomes. MRI serves as a critical tool in assessing treatment response. However, differentiating viable tumor tissue from therapy-induced changes on MRI remains a complex task. In this comprehensive review, we explore treatment options for rectal cancer based on resectability status, focusing on the role of MRI in guiding therapeutic decisions. We delve into the nuances of MRI-based evaluation of treatment response following neoadjuvant therapy, with particular attention to emerging techniques like radiomics. Drawing from current literature and insights, we provide essential recommendations for post-neoadjuvant therapy management in rectal cancer, all within the context of MRI-based findings.

Keywords

rectal cancer; neoadjuvant therapy; magnetic resonance imaging; treatment response

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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