Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Risk Factors for Intrauterine Fetal Death in Term Pregnancy – a Single Tertiary Clinic Study

Version 1 : Received: 21 October 2023 / Approved: 23 October 2023 / Online: 23 October 2023 (10:48:05 CEST)

A peer-reviewed article of this Preprint also exists.

Jovanovic, I.; Ivanovic, K.; Kostic, S.; Tadic, J.; Dugalic, S.; Petronijevic, M.; Gojnic, M.; Petronijevic, M.; Vrzic-Petronijevic, S. Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study. Life 2023, 13, 2320. Jovanovic, I.; Ivanovic, K.; Kostic, S.; Tadic, J.; Dugalic, S.; Petronijevic, M.; Gojnic, M.; Petronijevic, M.; Vrzic-Petronijevic, S. Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study. Life 2023, 13, 2320.

Abstract

Introduction: Intrauterine fetal death (IFD) is death of fetus after the 20th week of gestation. Despite regular monitoring, the incidence of IFD remains high. This study aims to assess the incidence and risk factors for IFD in term pregnancies for better prevention and reduction of neonatal morbidity and mortality. Materials and Methods: A retrospective cohort study was conducted with term pregnant women diagnosed with IFD. The analysis included the number of deliveries, live births, and stillbirths. Statistical analysis involves descriptive and analytical statistical methods. Results: Average age was 30 years. Most patients had intermediate and high education, and one-third of patients had regular pregnancy monitoring. 53.33% were primiparous, and pregnancies occurred spontaneously. IFD mainly occurred in the 39th week of gestation. The average birth weight was approximately 3000g. 38.3% had one to two associated diseases, 5% more than three, and 56.7% were healthy. Recurrence of IFD was reported by 10% of patients, while 8.33% had a history of spontaneous abortion. Over 80% of placental histopathological findings indicated some pathology (infarction, infections, abruptio placenta). Conclusion: The most significant risk factors were pregnancy-induced hypertensive disorders, obesity, and diabetes, followed by hypothyroidism, maternal tachycardia, and anemia.

Keywords

intrauterine fetal death; term pregnancies

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

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