Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Triterpene Glycosides from Cucumaria frondosa, a North Atlantic Mass Harvesting Sea Cucumber: A Comprehensive Structures and Biological Activities Review

Version 1 : Received: 13 October 2023 / Approved: 13 October 2023 / Online: 13 October 2023 (10:56:54 CEST)

How to cite: Kalinin, V.I.; Silchenko, A.S.; Avilov, S.A. Triterpene Glycosides from Cucumaria frondosa, a North Atlantic Mass Harvesting Sea Cucumber: A Comprehensive Structures and Biological Activities Review. Preprints 2023, 2023100884. https://doi.org/10.20944/preprints202310.0884.v1 Kalinin, V.I.; Silchenko, A.S.; Avilov, S.A. Triterpene Glycosides from Cucumaria frondosa, a North Atlantic Mass Harvesting Sea Cucumber: A Comprehensive Structures and Biological Activities Review. Preprints 2023, 2023100884. https://doi.org/10.20944/preprints202310.0884.v1

Abstract

The review concerns the chemical structures of all the triterpene glycosides from the most valuable commercially harvesting North Atlantic sea cucumber Cucumaria frondosa and their biological activities. The isolation and structural elucidation of 17 specific triterpene glycosides are described along with isolation and identification of two known glycosides. Antitumor, immunomodulatory, antithrombotic and anti-Alzheimer disease activities are also described. Frondoside A, the major component of the glycosidic fraction seems to be very perspective leader-compound for creation of useful medicinal preparations.

Keywords

sea cucumbers; Cucumaria frondosa; triterpene glycosides; frondosides; frondoside A; biological activity.

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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