Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cannabis induced psychosis: A comparative study between cannabis use disorder and cocaine use disorder

Version 1 : Received: 5 October 2023 / Approved: 6 October 2023 / Online: 6 October 2023 (11:10:47 CEST)

How to cite: Coppola, M.; Mondola, R. Cannabis induced psychosis: A comparative study between cannabis use disorder and cocaine use disorder. Preprints 2023, 2023100311. https://doi.org/10.20944/preprints202310.0311.v1 Coppola, M.; Mondola, R. Cannabis induced psychosis: A comparative study between cannabis use disorder and cocaine use disorder. Preprints 2023, 2023100311. https://doi.org/10.20944/preprints202310.0311.v1

Abstract

Psychosis can be defined as a combination of psychopathological symptoms including delusions and/or hallucinations without insight. Psychotic disorders may configure a primary psychiatric illness or represent the result of a functional/structural brain damage induced by substance use, neurological diseases or other medical conditions. They are multifactorial disorders in which genetic, environmental and gene-environment interaction factors contribute to the expressiveness of the symptoms. Among the environmental factors, psychotropic substances represent the most important removable facilitators of psychosis. In our study, we compared the prevalence of substance induced psychosis between a sample of patients affected by cannabis use disorder and a sample of patients affected by cocaine use disorder analyzing retrospectively the data of outpatients with no personal or family history of psychiatric illnesses.

Keywords

cannabis; Δ⁹-THC; induced psychosis; schizophrenia

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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