Version 1
: Received: 27 September 2023 / Approved: 28 September 2023 / Online: 29 September 2023 (04:12:41 CEST)
How to cite:
Ali, S.; Asghar, T.; Jan, M. I.; Ali, T. Biogenic Synthesis of Zinc Nanocomposites for Controlling Bacterial Pathogenesis and Photocatalytic Degradation of Toxic Water Wastes. Preprints2023, 2023092052. https://doi.org/10.20944/preprints202309.2052.v1
Ali, S.; Asghar, T.; Jan, M. I.; Ali, T. Biogenic Synthesis of Zinc Nanocomposites for Controlling Bacterial Pathogenesis and Photocatalytic Degradation of Toxic Water Wastes. Preprints 2023, 2023092052. https://doi.org/10.20944/preprints202309.2052.v1
Ali, S.; Asghar, T.; Jan, M. I.; Ali, T. Biogenic Synthesis of Zinc Nanocomposites for Controlling Bacterial Pathogenesis and Photocatalytic Degradation of Toxic Water Wastes. Preprints2023, 2023092052. https://doi.org/10.20944/preprints202309.2052.v1
APA Style
Ali, S., Asghar, T., Jan, M. I., & Ali, T. (2023). Biogenic Synthesis of Zinc Nanocomposites for Controlling Bacterial Pathogenesis and Photocatalytic Degradation of Toxic Water Wastes. Preprints. https://doi.org/10.20944/preprints202309.2052.v1
Chicago/Turabian Style
Ali, S., Muhammad Ishtiaq Jan and Tahir Ali. 2023 "Biogenic Synthesis of Zinc Nanocomposites for Controlling Bacterial Pathogenesis and Photocatalytic Degradation of Toxic Water Wastes" Preprints. https://doi.org/10.20944/preprints202309.2052.v1
Abstract
It is important to develop new antibacterial drugs since the emergence of bacterial resistance to available antibiotics. Metal nanoparticles have the potential to combat antibiotic resistance and are effective antibacterial agents. Here, we demonstrate the biogenic production of zinc nanoparticles using Rhododendron arboreum stem bark. The biosynthesized ZnNPs were characterized through different analytical techniques such as UV-vis, FTIR, EDX, SEM, and XRD. Clinical isolates such as E. coli, S. aureus, and K. pneumonia were used to check the antibacterial efficacy of the biosynthesized zinc nanoparticles. The MIC and MBC values against K. pneumonia, S. aureu, and E. coli were found to be 34±0.21 and 11.71±0.47, 47±0.11 and 23.86±0.84 and 94±0.18 and 40.43±0.16 µg/mL, respectively. It dramatically decreased the integrity of the cell membrane and markedly increased the permeability of both inner and outer membranes. The green synthesized ZnNPs have good catalytic activity. It degraded 65% of methyl orange dye within 6h when the mixture was kept in direct sunlight, thus demonstrating good photodegradation potential and can be employed as a good photocatalyst. According to these results, biosynthesized zinc nanoparticles could be a potential therapy option for controlling bacterial pathogenesis and an effective photocatalyst for the elimination of hazardous water contaminants.
Keywords
Bacterial resistance; Metal nanoparticles; Rhododendron arboreum; S. aureus; Cell membrane; Photocatalysis
Subject
Chemistry and Materials Science, Medicinal Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
