Version 1
: Received: 30 August 2023 / Approved: 30 August 2023 / Online: 31 August 2023 (08:44:53 CEST)
How to cite:
Torres-Riera, S.; Arboix, A.; Garcia-Eroles, L.; Sánchez-López, M. Predictive Clinical Factors of In-hospital Mortality in 506 consecutive Very Old Female Patients with Acute Ischemic Stroke. Preprints2023, 2023082108. https://doi.org/10.20944/preprints202308.2108.v1
Torres-Riera, S.; Arboix, A.; Garcia-Eroles, L.; Sánchez-López, M. Predictive Clinical Factors of In-hospital Mortality in 506 consecutive Very Old Female Patients with Acute Ischemic Stroke. Preprints 2023, 2023082108. https://doi.org/10.20944/preprints202308.2108.v1
Torres-Riera, S.; Arboix, A.; Garcia-Eroles, L.; Sánchez-López, M. Predictive Clinical Factors of In-hospital Mortality in 506 consecutive Very Old Female Patients with Acute Ischemic Stroke. Preprints2023, 2023082108. https://doi.org/10.20944/preprints202308.2108.v1
APA Style
Torres-Riera, S., Arboix, A., Garcia-Eroles, L., & Sánchez-López, M. (2023). Predictive Clinical Factors of In-hospital Mortality in 506 consecutive Very Old Female Patients with Acute Ischemic Stroke. Preprints. https://doi.org/10.20944/preprints202308.2108.v1
Chicago/Turabian Style
Torres-Riera, S., Luís Garcia-Eroles and María-José Sánchez-López. 2023 "Predictive Clinical Factors of In-hospital Mortality in 506 consecutive Very Old Female Patients with Acute Ischemic Stroke" Preprints. https://doi.org/10.20944/preprints202308.2108.v1
Abstract
Background: The oldest old people (≥ 85 years) represent the fastest growing age group in Western populations. Knowledge on early outcomes of acute ischemic stroke (AIS) in very old female patients remains limited. Methods: We assessed gender differences and female-specific clinical data and in-hospital mortality in very old patients with AIS. Acute cerebral infarction was diagnosed in 506 very old female patients from a total of 4,600 acute cerebrovascular infarctions available in an ongoing 24-year hospital stroke data bank. A comparative analysis of vital status at discharge (alive versus dead) was performed in terms of cardiovascular risk factors, clinical data, and early outcomes. Results: The overall in-hospital mortality rate was 20.4%. In multivariate analysis, sudden onset, altered level of consciousness, and neurological, respiratory, cardiological or hemorrhagic complications, and lacunar infarcts appeared to be independent predictors of in-hospital mortality. Conclusions: Female patients ≥85 years with AIS are an unfavorable subgroup of stroke patients with a high risk of early mortality, which may be due to comorbidity, stroke subtype distribution, and higher frequency of medical complications. However, the presence of lacunar infarcts showed a significant protective effect.
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
