Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox

Version 1 : Received: 13 August 2023 / Approved: 14 August 2023 / Online: 14 August 2023 (07:14:36 CEST)

How to cite: Zhang, Q.; Cao, Z.; Zhang, K. Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints 2023, 2023080984. https://doi.org/10.20944/preprints202308.0984.v1 Zhang, Q.; Cao, Z.; Zhang, K. Study to Determine the Effectiveness of Unilateral Total Lobectomy Plus Isthmectomy and Bilateral Total Lobectomy in Treating Thyroid Micropapillary Carcinoma Treated with Euthyrox. Preprints 2023, 2023080984. https://doi.org/10.20944/preprints202308.0984.v1

Abstract

Objective: To examine the effect of bilateral total lobectomy and unilateral total lobectomy on improving thyroid function in patients with thyroid micropapillary carcinoma treated with euthyrox. Methods: The study was conducted on 68 patients with thyroid micro papillary carcinoma treated with euthyroxwho had been surgically treated with euthyrox in our hospital between January 2018 and December 2019. On the basis of random number grouping, they were divided into control groups (n = 34, bilateral total lobectomy) and observation groups (n = 34, unilateral total lobectomy plus isthmectomy). Thyroid function, free triiodothyronine (FT3), thyroid hormone (TSH), and voice function (VHI score) of the two groups were compared.Results: In comparison to the control group, the observation group had shorter incision lengths, shorter operation times, and shorter hospital stays, as well as less intraoperative bleeding and drainage volume, and the difference was statistically significant (P < 0.05); As compared with the control group, the observation group had higher FT4 and FT3 levels as well as lower TSH levels, a statistically significant difference (P < 0.05).VHI scores of emotions, function, physiology, and other voice functions were significantly lower among the observation group than those of the control group (P < 0.05).Conclusion: A unilateral total lobectomy with adjacent isthmus resection in patients with thyroid micro papillary carcinoma can yield ideal results, accelerate the time taken for surgical rehabilitation, improve thyroid function, thereby improving voice quality, as well as improve the overall prognosis of the patient.

Keywords

Thyroid papillary carcinoma; Bilateral total lobectomy; Unilateral total lobectomy plus isthmectomy; Thyroid function; Treatment efficacy

Subject

Medicine and Pharmacology, Endocrinology and Metabolism

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.