PreprintArticleVersion 2Preserved in Portico This version is not peer-reviewed
The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study
Version 1
: Received: 3 August 2023 / Approved: 4 August 2023 / Online: 7 August 2023 (09:28:11 CEST)
Version 2
: Received: 15 August 2023 / Approved: 30 August 2023 / Online: 31 August 2023 (09:03:01 CEST)
How to cite:
Yoo, J.; Je, M.; Kim, Y.; Clifton, P.M. The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints2023, 2023080457. https://doi.org/10.20944/preprints202308.0457.v2
Yoo, J.; Je, M.; Kim, Y.; Clifton, P.M. The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints 2023, 2023080457. https://doi.org/10.20944/preprints202308.0457.v2
Yoo, J.; Je, M.; Kim, Y.; Clifton, P.M. The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints2023, 2023080457. https://doi.org/10.20944/preprints202308.0457.v2
APA Style
Yoo, J., Je, M., Kim, Y., & Clifton, P.M. (2023). The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study. Preprints. https://doi.org/10.20944/preprints202308.0457.v2
Chicago/Turabian Style
Yoo, J., Yoona Kim and Peter Marshall Clifton. 2023 "The Effects of a 12-Month Dried Plum Consumption on Bone Mineral Density and Bone Turnover Markers in Korean Postmenopausal Women with Osteopenia: A Randomized, Open-Labeled, Controlled Study" Preprints. https://doi.org/10.20944/preprints202308.0457.v2
Abstract
Consumption of prunes has been shown to slow bone loss after menopause in American women but there is no data on its effects in Asian women. 135 postmenopausal Korean women with osteopenia were randomized to 100g/day of prunes or no prunes with 600U vitamin D and 800mg of calcium for 12 months. Bone density was measured at baseline and 12 months in the lumbar spine, both hips and the L forearm. Serum levels of CTX and P1NP and vitamin D calcium and phosphate were measured at baseline, 6 and 12 months. PTH was measured at baseline if vitamin D was low Four women dropped out of each group over the 12 months. There was no difference between groups in blood measures or bone density in any region over the 12 month trial., In conclusion 100g/day of prunes has no effect in Korean woman on bone density or bone markers.
Keywords
bone density; DXA; PTX; P1NP; prunes; women
Subject
Medicine and Pharmacology, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received:
31 August 2023
Commenter:
Peter Clifton
Commenter's Conflict of Interests:
Author
Comment:
vit d amount changed to 800IU author affiliations changed Department of Orthopaedic Surgery, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, Republic of Korea, 22332. furim@hanmail.net(J.Y.) Department of Food and Nutrition, Gyeongsang National University, Jinju 52828, Korea. alsrud4687@naver.com (M.J.) Department of Food and Nutrition, Institute of Agriculture and Life Science,Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Gyeongsangnam-do, Republic of Korea. yoona.kim@gnu.ac.kr (Y.K.) School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia. peter.clifton@unisa.edu.au; Tel.: +61 8 8302 1357 (P.M.C.)
Commenter: Peter Clifton
Commenter's Conflict of Interests: Author
author affiliations changed
Department of Orthopaedic Surgery, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, Republic of Korea, 22332. furim@hanmail.net(J.Y.) Department of Food and Nutrition, Gyeongsang National University, Jinju 52828, Korea. alsrud4687@naver.com (M.J.) Department of Food and Nutrition, Institute of Agriculture and Life Science,Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Gyeongsangnam-do, Republic of Korea. yoona.kim@gnu.ac.kr (Y.K.) School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia. peter.clifton@unisa.edu.au; Tel.: +61 8 8302 1357 (P.M.C.)