Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Cognitive Profile of SARS-cov-2 Recovered Patients: A Comprehensive Analysis of Persistent Dysfunctions in Long COVID

Version 1 : Received: 26 July 2023 / Approved: 27 July 2023 / Online: 27 July 2023 (13:28:13 CEST)

How to cite: Lima, A.R.O.; Cavendish, B.; Pinto, B.S.; Pelosof, R.; Sousa, J.P.D.; Silva, P.H.R.D.; Bertola, L.; Batista, M.P.; Neto, A.A.D.; Brunoni, A.R.; Vidal, K.S.M.; Ventura, D.F. Cognitive Profile of SARS-cov-2 Recovered Patients: A Comprehensive Analysis of Persistent Dysfunctions in Long COVID. Preprints 2023, 2023071945. https://doi.org/10.20944/preprints202307.1945.v1 Lima, A.R.O.; Cavendish, B.; Pinto, B.S.; Pelosof, R.; Sousa, J.P.D.; Silva, P.H.R.D.; Bertola, L.; Batista, M.P.; Neto, A.A.D.; Brunoni, A.R.; Vidal, K.S.M.; Ventura, D.F. Cognitive Profile of SARS-cov-2 Recovered Patients: A Comprehensive Analysis of Persistent Dysfunctions in Long COVID. Preprints 2023, 2023071945. https://doi.org/10.20944/preprints202307.1945.v1

Abstract

Long Covid is a term used for patients who have recovered from COVID-19 but exhibit persistent cognitive dysfunction, including mental confusion, difficulties in attention, impairment in executive functions and slow movements, among other common symptoms. A study was conducted with 65 patients who had a positive RT-PCR diagnosis and reported symptoms of cognitive impairment, such as memory loss and attention difficulties after recovery. The patients underwent neuropsychological evaluation and completed questionnaires on cognition, mood, and quality of life. During the cognitive screening, 71% of the patients showed alterations, with deficits in visual memory (69%), language (54%), visuospatial construction (49%), verbal episodic memory (37%), executive functions (36%), attentional abilities (34%), and premorbid intelligence (12%). It is important to highlight the need for treatments and further studies to understand the long-term side effects of this disease.

Keywords

memory loss; long COVID; post COVID; depression; mental confusion; COVID-19

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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