Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recent Advances in Combating Bacterial Infections by Using Hybrid Nano-systems

Version 1 : Received: 26 July 2023 / Approved: 27 July 2023 / Online: 27 July 2023 (13:06:30 CEST)

A peer-reviewed article of this Preprint also exists.

Patel, U.; Hunt, E.C. Recent Advances in Combating Bacterial Infections by Using Hybrid Nano-Systems. J. Nanotheranostics 2023, 4, 429-462. Patel, U.; Hunt, E.C. Recent Advances in Combating Bacterial Infections by Using Hybrid Nano-Systems. J. Nanotheranostics 2023, 4, 429-462.

Abstract

In recent years, antimicrobial resistance in many human pathogens has become a serious health concern. Since infections with resistant pathogens cannot be treated with traditional antimicro-bial drugs, new strategies are necessary to fight bacterial infections. Hybrid nano-systems may provide a solution to this problem, by combining multiple mechanisms for killing bacteria to synergistically increase the effectiveness of the antimicrobial treatment. In this review, we high-light recent advances in the development of hybrid nano-systems for the treatment of bacterial infections. We discuss the use of hybrid nano-systems for combinational therapy, focusing on various triggering mechanisms for drug release and the development of biomimetic nanomateri-als. We also examine inherently antimicrobial nano-systems and their uses in preventing infec-tions due to wounds and medical implants. This review summarizes recent advances and pro-vides insight into the future development of antimicrobial treatments using hybrid nanomateri-als.

Keywords

Stimuli-triggered nano-systems; hybrid nano-systems; biomimetics; bacterial infections

Subject

Chemistry and Materials Science, Nanotechnology

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