Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

The heterogeneity of diabetes, a silent pandemic: the essence of one health approach and precision medicine in the fight against diabetes

Version 1 : Received: 13 July 2023 / Approved: 13 July 2023 / Online: 14 July 2023 (09:55:58 CEST)

How to cite: Marshall, K.; Bu, S. The heterogeneity of diabetes, a silent pandemic: the essence of one health approach and precision medicine in the fight against diabetes. Preprints 2023, 2023070959. https://doi.org/10.20944/preprints202307.0959.v1 Marshall, K.; Bu, S. The heterogeneity of diabetes, a silent pandemic: the essence of one health approach and precision medicine in the fight against diabetes. Preprints 2023, 2023070959. https://doi.org/10.20944/preprints202307.0959.v1

Abstract

Life is supported by metabolism, a vital physiological activity. It guarantees enough energy available to power every cellular activity. The primary cellular substrate, glucose, is where the majority of the energy needed by the cell to support all other life activities and the growth of living creatures is derived. The quality of life is greatly impacted by any disease or flaw that alters the metabolism of glucose. There is no known cure for the metabolic illness known as diabetes. As diabetes is so varied, the only effective treatments would be based on precision medicine and a molecular strategy. This review covers a wide range of topics, including the ability to recognize the various forms of diabetes, the anthropogenic and genetic influence of the cause of diabetes, the severity of the various forms of diabetes, its potential existential risk, the disease burden, and clinical methods for diagnosing them. The most recent research goes on to recommend ways to ameliorate the disease, including diet-based management, biotherapies, and other individual lifestyle choices. Futuristic therapy using molecular biology approach was suggested. Recent research found a direct correlation between an individual's lifestyle and the rate of gene mutation in diabetes. There is an existential risk associated with the sickness as the rate of the spread of the disease among population globally is faster than the world's population growth rate. It is possible to think of diabetes as a silent pandemic.

Keywords

Diabetes mellitus; silent pandemic; existential risk; heterogeneity; Insulin gene; health, genetic; anthropogenics; hyperglycemia

Subject

Biology and Life Sciences, Endocrinology and Metabolism

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