Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Conceptual Independence of Health Status, Respiratory Symptoms and Dyspnea in Chronic Obstructive Pulmonary Dis-Ease in Real Clinical Practice

Version 1 : Received: 14 June 2023 / Approved: 14 June 2023 / Online: 14 June 2023 (07:47:07 CEST)

A peer-reviewed article of this Preprint also exists.

Nishimura, K.; Kusunose, M.; Mori, M.; Shibayama, A.; Nakayasu, K. The Conceptual Independence of Health Status, Respiratory Symptoms and Dyspnea in Chronic Obstructive Pulmonary Disease in Real Clinical Practice. Diagnostics 2023, 13, 2492. Nishimura, K.; Kusunose, M.; Mori, M.; Shibayama, A.; Nakayasu, K. The Conceptual Independence of Health Status, Respiratory Symptoms and Dyspnea in Chronic Obstructive Pulmonary Disease in Real Clinical Practice. Diagnostics 2023, 13, 2492.

Abstract

The hypothesis that health status is the highest-ranking concept, followed by respiratory symptoms and dyspnea as the lowest-ranking concepts in subjects with chronic obstructive pulmonary disease (COPD) was tested in a real clinical setting with 157 subjects with stable COPD. Spearman's rank correlation coefficients for scores of health status using the COPD assessment test (CAT), respiratory symptoms using the COPD Evaluating Respiratory Symptoms (E-RS) and dyspnea using the Dyspnoea-12 (D-12) between any two were 0.6 to 0.7. Upon categorizing the patients as "abnormal" or "normal" according to the threshold, it was found that 30 patients (19.1%) had dyspnea, respiratory symptoms, and impaired the health status. Dyspnea was considered an important part of respiratory symptoms though seven patients had dyspnea but no respiratory symptoms. There were 10 patients who had respiratory symptoms without dyspnea but without health status problems. Furthermore, there were six patients who had both dyspnea and respiratory symptoms but whose health status was classified as fine. Thus, the hypothesis was correct in approximately 85% of cases.

Keywords

COPD; Dyspnea; Health Status; Respiratory Symptoms; Surveys and Questionnaires

Subject

Medicine and Pharmacology, Pulmonary and Respiratory Medicine

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