Version 1
: Received: 7 June 2023 / Approved: 7 June 2023 / Online: 7 June 2023 (08:05:43 CEST)
How to cite:
Shama, M.; Mahmood, A.; Mehmood, S.; Zhang, W. Pathological Effects of SARS-CoV-19 Associated With Hematological Abnormalities. Preprints2023, 2023060508. https://doi.org/10.20944/preprints202306.0508.v1
Shama, M.; Mahmood, A.; Mehmood, S.; Zhang, W. Pathological Effects of SARS-CoV-19 Associated With Hematological Abnormalities. Preprints 2023, 2023060508. https://doi.org/10.20944/preprints202306.0508.v1
Shama, M.; Mahmood, A.; Mehmood, S.; Zhang, W. Pathological Effects of SARS-CoV-19 Associated With Hematological Abnormalities. Preprints2023, 2023060508. https://doi.org/10.20944/preprints202306.0508.v1
APA Style
Shama, M., Mahmood, A., Mehmood, S., & Zhang, W. (2023). Pathological Effects of SARS-CoV-19 Associated With Hematological Abnormalities. Preprints. https://doi.org/10.20944/preprints202306.0508.v1
Chicago/Turabian Style
Shama, M., Shahid Mehmood and Wen Zhang. 2023 "Pathological Effects of SARS-CoV-19 Associated With Hematological Abnormalities" Preprints. https://doi.org/10.20944/preprints202306.0508.v1
Abstract
The SARS coronavirus 2 (SARS-CoV-2) is the causative agent of the 2019 coronavirus disease (COVID-19) pandemic that has executed 6.9 million people and infected over 765 million. It’s become a major worldwide health alarm and is also known to cause abnormalities in various systems, including the hematologic system. COVID-19 infection primarily affects the lower res-piratory tract and can lead to a cascade of events, including a cytokine storm, intravascular thrombosis, and subsequent complications such as arterial and venous thromboses. COVID-19 can cause thrombocytopenia, lymphopenia, and neutrophilia, which are associated with worse out-comes. Prophylactic anticoagulation is essential to prevent complication and death rate associated with the virus's effect on the coagulation system. It is crucial to recognize these complications early and promptly start therapeutic anticoagulation to improve patient outcomes. While rare, COVID-19-induced disseminated intravascular coagulation exhibits some similarities to DIC induced by sepsis. LDH, D-dimer, ferritin, and CRP biomarker are often increase in serious COVID-19 cases and poor prognosis. Understanding the pathophysiology of the disease and identifying risk factors for adverse outcomes is critical for effective management of COVID-19.
Keywords
SARS-CoV-2; Hematology; COVID-19; Biomarkers
Subject
Public Health and Healthcare, Public Health and Health Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
