Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Current Development of Bio-inspired Nanoparticles in Cancer Theragnostics

Version 1 : Received: 31 May 2023 / Approved: 1 June 2023 / Online: 1 June 2023 (07:54:20 CEST)

A peer-reviewed article of this Preprint also exists.

Tripathi, D.; Hajra, K.; Maity, D. Recent Advancement of Bio-Inspired Nanoparticles in Cancer Theragnostic. J. Nanotheranostics 2023, 4, 299-322. Tripathi, D.; Hajra, K.; Maity, D. Recent Advancement of Bio-Inspired Nanoparticles in Cancer Theragnostic. J. Nanotheranostics 2023, 4, 299-322.

Abstract

The introduction of cancer therapeutics and nanotechnology has resulted in a paradigm shift from conventional therapy to precision medicine. Nanotechnology, an interdisciplinary field with a focus on biomedical applications, holds immense promise in bringing about novel approaches for cancer detection, diagnosis, and therapy. The past decade has witnessed significant research and material applications related to nanoparticles (NPs). NPs differ from small-molecule drugs as they possess unique physicochemical characteristics, such as a large surface-to-volume ratio, enabling them to penetrate live cells efficiently. Traditional cancer therapies, such as chemotherapy, radiation therapy, targeted therapy, and immunotherapy, have limitations, such as cytotoxicity, lack of specificity, and multiple drug resistance, which pose significant challenges for effective cancer treatment. However, nanomaterials have unique properties that enable new therapeutic modalities beyond conventional drug delivery in the fight against cancer. Moreover, nanoparticles (1-100 nm) have numerous benefits, such as biocompatibility, reduced toxicity, excellent stability, enhanced permeability and retention effect, and precise targeting, making them ideal for cancer treatment. The purpose of this article is to provide consolidated information on various bio-inspired nanoparticles that aid in cancer theragnostics.

Keywords

Nanoparticles; Quantum dots; Radioisotopes; Liposomes; Micelles; Nanobubbles; Theranostics; Therapeutics; Toxicity

Subject

Biology and Life Sciences, Biology and Biotechnology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.