Preprint Hypothesis Version 1 Preserved in Portico This version is not peer-reviewed

Use of Rotavirus Vaccine as a Containment Measure for SARS- CoV-2 Coronavirus (COVID-19): A Study of Possible Cross and Trained Immunity

Version 1 : Received: 26 May 2023 / Approved: 29 May 2023 / Online: 29 May 2023 (09:29:18 CEST)

How to cite: Lorite - Ayan, N. Use of Rotavirus Vaccine as a Containment Measure for SARS- CoV-2 Coronavirus (COVID-19): A Study of Possible Cross and Trained Immunity. Preprints 2023, 2023052002. https://doi.org/10.20944/preprints202305.2002.v1 Lorite - Ayan, N. Use of Rotavirus Vaccine as a Containment Measure for SARS- CoV-2 Coronavirus (COVID-19): A Study of Possible Cross and Trained Immunity. Preprints 2023, 2023052002. https://doi.org/10.20944/preprints202305.2002.v1

Abstract

This proposal was prepared in the very first weeks of 2020 because of the outbreak of COVID-19. There are good reasons to suppose that rotavirus vaccine can be used as protection tool to effectively and safely fight and mitigate SARS-CoV-2 infection and the impact caused by COVID- 19 in adult humans, due to the development of cross and trained immunity following rotavirus vaccination. Up-to-date, some rotavirus vaccines are available and approved, two of them have a large experience in results and safety. Little experience has been achieved in the use of rotavirus vaccine in adults. However, it can be expected that it would be safe and effective in adults and in the elderly as well. This proposal explains the background of this hypothesis based on lungs and intestine relationships.

Keywords

rotavirus; coronavirus; vaccine; SARS-CoV-2; COVID-19; cross immunity; trained immunity; vaccinated breakthrough infections; COVID variants; long-Covid

Subject

Medicine and Pharmacology, Immunology and Allergy

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