Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Benzoic Acid and It’s Synthetic Derivatives as Important Medicinal Product Attenuates Cancer: an Up-to-date Review

Version 1 : Received: 26 May 2023 / Approved: 29 May 2023 / Online: 29 May 2023 (05:00:08 CEST)

How to cite: Kumar, A.; YT, K.; Singh, M.; Singh, H.; Kaushik, N.; Mishra, A.; Mishra, A.K. Benzoic Acid and It’s Synthetic Derivatives as Important Medicinal Product Attenuates Cancer: an Up-to-date Review. Preprints 2023, 2023051969. https://doi.org/10.20944/preprints202305.1969.v1 Kumar, A.; YT, K.; Singh, M.; Singh, H.; Kaushik, N.; Mishra, A.; Mishra, A.K. Benzoic Acid and It’s Synthetic Derivatives as Important Medicinal Product Attenuates Cancer: an Up-to-date Review. Preprints 2023, 2023051969. https://doi.org/10.20944/preprints202305.1969.v1

Abstract

Cancer is a catchall term that refers to a collection of more than one chronic disease that can adversely affect the body, including the organs of the body. These diseases can be grouped together under the umbrella term "cancer." Cancer is a catch-all term that is used to refer to a number of different diseases. During the process of looking for new chemical entities, it was found that certain compounds with a basic nucleus of benzoic acid (BA) exhibit a remarkable anticancer potential. This was discovered while the researchers were looking for new chemical entities. In the sixteenth century, the aromatic chemical known as BA, which is also known as an aromatic carboxylic acid, was discovered. BA is also referred to as an aromatic carboxylic acid. When it comes to the chemical synthesis of a wide range of different active molecules, the utilization of a sizeable quantity of BA as a raw material is absolutely necessary. In addition to being present in a variety of other naturally occurring compounds, the BA moiety is the component that is responsible for the activity of the naturally occurring compounds vanillin, gallic acid, and syringic acid. In the synthesis of a wide variety of synthetic bioactive molecules, the BA scaffold is utilized as a building block. The drugs furosemide, bumetanide, benzocaine, tetracaine, and bexarotene are all examples of molecules that fall into this category. The scope of this review article allows for the discussion of a number of noteworthy and recent achievements of BA derivatives in terms of their effectiveness against cancer.

Keywords

Cancer; Benzoic acid; Anti-cancer activity; Scaffold

Subject

Public Health and Healthcare, Public, Environmental and Occupational Health

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