Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Expanded PCR Panel Testing for Identification of Respiratory Pathogens and Coinfections in Influenza-like Illness

Version 1 : Received: 17 May 2023 / Approved: 18 May 2023 / Online: 18 May 2023 (14:10:38 CEST)

A peer-reviewed article of this Preprint also exists.

Upadhyay, P.; Reddy, J.; Proctor, T.; Sorel, O.; Veereshlingam, H.; Gandhi, M.; Wang, X.; Singh, V. Expanded PCR Panel Testing for Identification of Respiratory Pathogens and Coinfections in Influenza-like Illness. Diagnostics 2023, 13, 2014. Upadhyay, P.; Reddy, J.; Proctor, T.; Sorel, O.; Veereshlingam, H.; Gandhi, M.; Wang, X.; Singh, V. Expanded PCR Panel Testing for Identification of Respiratory Pathogens and Coinfections in Influenza-like Illness. Diagnostics 2023, 13, 2014.

Abstract

Respiratory tract infections (RTIs) are one of the main causes of hospitalization and mortality causing substantial economic burden to healthcare systems globally. As opposed to the previous belief that respiratory infections are caused by a single pathogen, studies have shown that most RTIs are a result of a combination of bacterial and/or viral pathogens infecting the host. The clinical manifestation of RTIs is very similar (i.e., syndrome), often showing Influenza-like illness (ILI) symptoms. While COVID-19 has dominated ILI over the past few years, there are many other pathogens that are responsible for ILI. In addition, it is not uncommon to have coinfections with multiple pathogens in patients presenting with ILI and that such coinfections can even exacerbate the disease severity of RTIs. Therefore, an insight into coinfections can help with accurate disease prognosis, patient care management and outcomes. The goal of this study was to identify the different organisms in symptomatic patients presenting with ILI.

Keywords

Respiratory tract infections; COVID-19; influenza-like illness; multiplex PCR; syndromic panels

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.