Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Is the Identification of Multiple Infantile Cutaneous Hemangiomas Always a Definitive Diagnosis? A Case Report of an Infant with a Multifocal Hepatic Hemangioma (MHH)

Version 1 : Received: 16 May 2023 / Approved: 17 May 2023 / Online: 17 May 2023 (02:55:53 CEST)

How to cite: Baranowska, J.; Boral, W.; Jarzumbek, A.; Kluczewska, E.; Saran, A.; Kwiecień, J.; Górowska-Kowolik, K.; Grabowski, A.; Sienko, A.; Bąk-Drabik, K. Is the Identification of Multiple Infantile Cutaneous Hemangiomas Always a Definitive Diagnosis? A Case Report of an Infant with a Multifocal Hepatic Hemangioma (MHH). Preprints 2023, 2023051172. https://doi.org/10.20944/preprints202305.1172.v1 Baranowska, J.; Boral, W.; Jarzumbek, A.; Kluczewska, E.; Saran, A.; Kwiecień, J.; Górowska-Kowolik, K.; Grabowski, A.; Sienko, A.; Bąk-Drabik, K. Is the Identification of Multiple Infantile Cutaneous Hemangiomas Always a Definitive Diagnosis? A Case Report of an Infant with a Multifocal Hepatic Hemangioma (MHH). Preprints 2023, 2023051172. https://doi.org/10.20944/preprints202305.1172.v1

Abstract

Multifocal hepatic hemangiomas (MHHs) are the most common benign vascular tumours of the liver that are detected in children with concomitant multiple infantile hemangiomas. They still pose a diagnostic problem for GPs and are thus often detected far too late, due to their low prevalence rates. MHHs are usually undetectable at birth, usually detected within the first few weeks of life when the lesions proliferate. The heterogeneity of the lesions and the presence of comorbidities make often the management of infantile hepatic hemangiomas a true challenge, also for highly specialised medical professionals. Ultrasound (USG) should be the imaging examination performed in the first instance in search for vascular anomalies in children. In pharmacotherapy, the first choice treatment is propranolol and prednisone, administered orally. Invasive treatment is usually indicated in symptomatic or progressive multiple hepatic hemangiomas only. Recently published studies show a significant decrease in the incidence rate of the disease, which now ranges between 11% and 18% for treated and untreated hepatic hemangiomas, respectively.

Keywords

multifocal hepatic hemangioma; infant hemangioma; infant hepatic hemangioma; propranolol

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

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