The Importance of Entomo-Virological Investigation of Yellow Fever Virus to Strength Surveillance in Brazil

Ana Cecília Ribeiro Cruz; Leonardo Henrique Almeida Hernández; Carine Fortes Aragão; Thito Yan Bezerra Da Paz; Sandro Patroca da Silva; Fábio Silva da Silva; Ana Alice Aquino; Glennda Juscely Galvão Pereira Cereja; Bruna Lais Sena do Nascimento; José Wilson Rosa Junior Rosa Junior; Carmeci Natalina Elias; Cristiano Gomes Nogueira; Daniel Garkauskas Ramos; Vagner Fonseca; Marta Giovanetti; Luiz Carlos Junior Alcantara; Bruno Tardelli Diniz Nunes; Pedro F. da Costa Vasconcelos; Livia Carício Martins; Joaquim Pinto Nunes-Neto

doi:10.20944/preprints202305.0969.v1

Submit preprint
How it Works
Instructions for Authors
Subject Areas
Advisory Board
screening preprints
About
Awards
Log in/Register

Instructions for Authors
Awards
About
FAQ
Submit Log in/Register

Share this article with

Create alert

Email:

Load new image

preprints.org > biology and life sciences > virology > doi: 10.20944/preprints202305.0969.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Importance of Entomo-Virological Investigation of Yellow Fever Virus to Strength Surveillance in Brazil

Ana Cecília Ribeiro Cruz

^* ,

Leonardo Henrique Almeida Hernández

Carine Fortes Aragão

Thito Yan Bezerra Da Paz

Sandro Patroca da Silva

Fábio Silva da Silva

Ana Alice Aquino

Glennda Juscely Galvão Pereira Cereja

Bruna Lais Sena do Nascimento

José Wilson Rosa Junior Rosa Junior

Carmeci Natalina Elias

Cristiano Gomes Nogueira

Daniel Garkauskas Ramos

Vagner Fonseca

Marta Giovanetti

Luiz Carlos Junior Alcantara

Bruno Tardelli Diniz Nunes

Pedro F. da Costa Vasconcelos

Livia Carício Martins

Joaquim Pinto Nunes-Neto

Version 1 : Received: 12 May 2023 / Approved: 15 May 2023 / Online: 15 May 2023 (03:25:34 CEST)

A peer-reviewed article of this Preprint also exists.

Cruz, A.C.R.; Hernández, L.H.A.; Aragão, C.F.; da Paz, T.Y.B.; da Silva, S.P.; da Silva, F.S.; de Aquino, A.A.; Cereja, G.J.G.P.; Nascimento, B.L.S.; Rosa Junior, J.W.; Elias, C.N.; Nogueira, C.G.; Ramos, D.G.; Fonseca, V.; Giovanetti, M.; Alcantara, L.C.J.; Nunes, B.T.D.; Vasconcelos, P.F.C.; Martins, L.C.; Nunes-Neto, J.P. The Importance of Entomo-Virological Investigation of Yellow Fever Virus to Strengthen Surveillance in Brazil. Trop. Med. Infect. Dis. 2023, 8, 329. Cruz, A.C.R.; Hernández, L.H.A.; Aragão, C.F.; da Paz, T.Y.B.; da Silva, S.P.; da Silva, F.S.; de Aquino, A.A.; Cereja, G.J.G.P.; Nascimento, B.L.S.; Rosa Junior, J.W.; Elias, C.N.; Nogueira, C.G.; Ramos, D.G.; Fonseca, V.; Giovanetti, M.; Alcantara, L.C.J.; Nunes, B.T.D.; Vasconcelos, P.F.C.; Martins, L.C.; Nunes-Neto, J.P. The Importance of Entomo-Virological Investigation of Yellow Fever Virus to Strengthen Surveillance in Brazil. Trop. Med. Infect. Dis. 2023, 8, 329.

Abstract

After eight decades, the largest outbreak of sylvatic yellow fever virus (YFV) was recorded in Brazil between 2016-2018. Besides human and NHP surveillance, the entomo-virological approach is considered as a complementary tool. For this study, a total of 2904 mosquitoes of Aedes, Haemagogus and Sabethes genera from six Brazilian states (Bahia, Goiás, Mato Grosso, Minas Gerais, Pará, and Tocantins), were collected and grouped in 246 pools, which were tested for YFV using RT-qPCR. We detected 20 positive pools from Minas Gerais, 5 from Goiás, and 1 from Bahia, including 12 of Hg. janthinomys and 5 of Ae. albopictus. This is the first description of natural YFV infection in this species and warns of the likelihood of urban YFV re-emergence with the Ae. albopictus as a potential bridge vector. Three YFV sequences from Hg. janthinomys from Goiás and one from Minas Gerais, as well as one from Ae. albopictus from Minas Gerais clustered within the 2016-2018 outbreak clade, indicating YFV spread from Midwest and its infection in a main and in a likely-novel bridging vector species. Entomo-virological surveillance is critical in the YFV monitoring in Brazil, which could highlight the need to strengthen YFV surveillance, vaccination coverage, and vector control measures.

Keywords

yellow fever virus; vectors; Aedes albopictus; outbreak; entomo-virological surveillance

Subject

Biology and Life Sciences, Virology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF Download Supplementary

Comments (0)

Not displayed online.

Importance: How significant is the paper to the field?

Outstanding/highlight paper

Significant contribution

Incremental contribution

No contribution

I am not qualified to judge

Soundness of evidence/arguments presented:

Conclusions well supported

Most conclusions supported (minor revision needed)

Incomplete evidence (major revision needed)

Hypothesis, unsupported conclusions, or proof-of-principle

I am not qualified to judge

Please leave your comment to this article below.

Mathematical equations can be typed in either LaTeX formats \\[ ... \\] or $$ ... $$, or MathML format <math> ... </math>. Try the LaTeX or MathML example.

Type equation:

Preview:

Copy equation into message below

Close menu

Please click a symbol to insert it into the message box below:

Please enter the link here:

Please enter a valid URL

Optionally, you can enter text that should appear as linked text:

Copy link into message below

Close menu

Please enter or paste the URL to the image here (please only use links to jpg/jpeg, png and gif images):

Please enter a valid URL

Copy image into message below

Close menu

Type author name or keywords to filter the list of references in this group (you can add a new citation under Bibliography):

No existing citations in Discussion Group

Wikify editor is a simple editor for wiki-style mark-up. It was written by MDPI for Sciforum in 2014. The rendering of the mark-up is based on Wiky.php with some tweaks. Rendering of mathematical equations is done with MathJax. Please send us a message for support or for reporting bugs.

Close menu

Please declare any conflicts of interest you may have with this paper, financial or otherwise.

I do not have a conflict of interest

I would like to declare a conflict of interest

Display my name on the website Send my name and email address to the authors

Captcha

Renew

I accept the following conditions:

Comments must follow the standards of professional discourse and should focus on the scientific content of the article. Insulting or offensive language, personal attacks and off-topic remarks will not be permitted. Comments must be written in English. Preprints reserves the right to remove comments without notice. Readers who post comments are obliged to declare any competing interests, financial or otherwise.

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)

* All users must log in before leaving a comment

what’s this?

Add a record of this review to Publons to track and showcase your reviewing expertise across the world’s journals.

Downloads 0

Comments 0

Metrics 0

Get PDF Supplementary Files Cite Share 0

Bookmark BibSonomy Mendeley Reddit Delicious

Alerts

Notify me about updates to this article or when a peer-reviewed version is published.

Preprints.org is a free preprint server subsidized by MDPI in Basel, Switzerland.

MDPI Initiatives

SciProfiles
Sciforum
Encyclopedia
MDPI Books
Scilit
Proceedings
JAMS

Important links

How it Works
Advisory Board
FAQ
Friendly Journals
Instructions for Authors
About
Statistics

Choose the area that interest you and we will send you notifications of new preprints at your preferred frequency.

Disclaimer

We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.

RSS feed for

Preprints: The Multidisciplinary Preprint Platform

Paste the URL in your RSS reader:

https://www.preprints.org/rss

If you want to subscribe our website in subject-wide, you could find the URL by choosing in the following:

https://www.preprints.org/rss

Please note that by using ScienceDirect RSS feeds, you agree to our Terms of Use and Privacy Policy.