Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Unraveling Peritoneal Carcinomatosis on Cross-Sectional Imaging Modalities

Version 1 : Received: 8 May 2023 / Approved: 9 May 2023 / Online: 9 May 2023 (05:49:01 CEST)

A peer-reviewed article of this Preprint also exists.

Veron Sanchez, A.; Bennouna, I.; Coquelet, N.; Cabo Bolado, J.; Pinilla Fernandez, I.; Mullor Delgado, L.A.; Pezzullo, M.; Liberale, G.; Gomez Galdon, M.; Bali, M.A. Unravelling Peritoneal Carcinomatosis Using Cross-Sectional Imaging Modalities. Diagnostics 2023, 13, 2253. Veron Sanchez, A.; Bennouna, I.; Coquelet, N.; Cabo Bolado, J.; Pinilla Fernandez, I.; Mullor Delgado, L.A.; Pezzullo, M.; Liberale, G.; Gomez Galdon, M.; Bali, M.A. Unravelling Peritoneal Carcinomatosis Using Cross-Sectional Imaging Modalities. Diagnostics 2023, 13, 2253.

Abstract

Among cross-sectional imaging modalities, computed tomography (CT) is more available and faster; however, magnetic resonance (MR) performs better in terms of sensitivity and specificity, due to its higher contrast resolution. The appearance of peritoneal deposits on CT and MR depends mainly on the primary tumour histology: in case of unknown primary tumour (3-5% of cases), their behaviour at imaging may provide insights on the tumour origin. The time-point of tumour evolution, previous or ongoing treatments and the peritoneal spaces where they occur, also play an important role in determining the appearance of peritoneal deposits. Thus, knowledge of peritoneal anatomy and fluid circulation is mandatory in detection and characterization of peritoneal deposits. Several benign and malignant conditions may show similar imaging features that overlap those of PC, making the differential diagnosis challenging. Clinical history, laboratory findings and previous imaging examinations must be considered to achieve the correct diagnosis.

Keywords

peritoneum 1; carcinomatosis 2; deposits 3

Subject

Medicine and Pharmacology, Medicine and Pharmacology

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