Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Long-Term Comparison of Two- and Three-Dimensional Computed Tomography Analyses of Cranial Bone Defects in Severe Parietal Thinning

Johannes Dominikus Pallua
* ORCID logo ,
Anton Kasper Pallua
,
Werner Streif
,
Harald Spiegl
,
Clemens Halder
,
Rohit ARORA
,
Michael Schirmer
* ORCID logo
Version 1 : Received: 21 April 2023 / Approved: 23 April 2023 / Online: 23 April 2023 (03:42:25 CEST)

A peer-reviewed article of this Preprint also exists.

Pallua, J.D.; Pallua, A.K.; Streif, W.; Spiegl, H.; Halder, C.; Arora, R.; Schirmer, M. Long-Term Comparison of Two- and Three-Dimensional Computed Tomography Analyses of Cranial Bone Defects in Severe Parietal Thinning. Diagnostics 2024, 14, 446, doi:10.3390/diagnostics14040446. Pallua, J.D.; Pallua, A.K.; Streif, W.; Spiegl, H.; Halder, C.; Arora, R.; Schirmer, M. Long-Term Comparison of Two- and Three-Dimensional Computed Tomography Analyses of Cranial Bone Defects in Severe Parietal Thinning. Diagnostics 2024, 14, 446, doi:10.3390/diagnostics14040446.

Abstract

Quantification of bone loss for follow-up comparisons has not been routinely performed in patients with parietal thinning so far. This study compares different methodological approaches including both 2- and 3-dimensional methods in computerized tomographies of a single patient. The 2-dimensional method provides accurate measurements of bone thickness, while the 3-dimensional method allows for a more comprehensive view of the bone's structure, including parameters like shape, size, and thickness. The techniques provided valuable data for the treating physician and suggest a possible effect of corticosteroids in this individual patient. The study concludes that 3-dimensional reconstruction of computerized tomographies with subsequent 2-dimensional analyses appears justified for routine radiological practice to increase clinical awareness of the size of the parietal bone defects and allow for quantification of bone loss during long-term follow-ups. Further validation of the proposed analytical approaches is warranted in larger studies to investigate patterns of bone thinning across the skull and changes in bone volumes over time, with specialized software to be approved for such analyses.

Keywords

parietal thinning; measurement reliability; bone defects; magnetic resonance imaging; computer tomography; osteology; rheumatology; rare disease

Subject

Medicine and Pharmacology, Clinical Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.