PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Higher Penetration Depth of 1064 NM Compared to 905 NM Laser Light Into Biological Tissue Is Only Relevant for Surface Layers and Insignificant for 10 MM Tissue Depth Onwards
Version 1
: Received: 8 March 2023 / Approved: 9 March 2023 / Online: 9 March 2023 (11:03:09 CET)
How to cite:
Kaub, L.; Schmitz, C. Higher Penetration Depth of 1064 NM Compared to 905 NM Laser Light Into Biological Tissue Is Only Relevant for Surface Layers and Insignificant for 10 MM Tissue Depth Onwards. Preprints2023, 2023030176. https://doi.org/10.20944/preprints202303.0176.v1.
Kaub, L.; Schmitz, C. Higher Penetration Depth of 1064 NM Compared to 905 NM Laser Light Into Biological Tissue Is Only Relevant for Surface Layers and Insignificant for 10 MM Tissue Depth Onwards. Preprints 2023, 2023030176. https://doi.org/10.20944/preprints202303.0176.v1.
Cite as:
Kaub, L.; Schmitz, C. Higher Penetration Depth of 1064 NM Compared to 905 NM Laser Light Into Biological Tissue Is Only Relevant for Surface Layers and Insignificant for 10 MM Tissue Depth Onwards. Preprints2023, 2023030176. https://doi.org/10.20944/preprints202303.0176.v1.
Kaub, L.; Schmitz, C. Higher Penetration Depth of 1064 NM Compared to 905 NM Laser Light Into Biological Tissue Is Only Relevant for Surface Layers and Insignificant for 10 MM Tissue Depth Onwards. Preprints 2023, 2023030176. https://doi.org/10.20944/preprints202303.0176.v1.
Abstract
The choice of parameters for laser beams used in the treatment of musculoskeletal diseases is of great importance. First, to reach high penetration depths into biological tissue and, secondly, to achieve the required effects on a molecular level. The penetration depth depends on the wavelength since there are multiple light-absorbing and scattering molecules in tissue with different absorption spectra. The present study is the first comparing the penetration depth of 1064 nm laser light with light of a smaller wavelength (905 nm) using high-fidelity laser measurement technology. Penetration depths in two types of tissue (porcine skin and bovine muscle) were investigated. The transmittance of 1064 nm light through both tissue types was consistently higher than of 905 nm light. The largest differences (up to 5.9%) were seen in the upper 10 mm of tissue, while the difference vanished with increasing tissue thickness. The higher penetration was most likely due to a combination of lower absorption in hemoglobin and less scattering at larger wavelengths, and not due to absorption in melanin. Overall, differences in penetration depth were comparably small and high peak power and short pulse lengths of laser light seem to be more important to efficiently treat deep musculoskeletal diseases.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
