PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Pharmacological Prescription for Atrial Fibrillation, Dyslipidemia and Hypertension: Observational Analytical #TRIGERIA Study in Institutionalized Patients
Version 1
: Received: 8 February 2023 / Approved: 13 February 2023 / Online: 13 February 2023 (07:21:50 CET)
How to cite:
Esquirol Caussa, J.; Herrero Vila, E.; Sánchez Aldeguer, J. Pharmacological Prescription for Atrial Fibrillation, Dyslipidemia and Hypertension: Observational Analytical #TRIGERIA Study in Institutionalized Patients. Preprints2023, 2023020202. https://doi.org/10.20944/preprints202302.0202.v1.
Esquirol Caussa, J.; Herrero Vila, E.; Sánchez Aldeguer, J. Pharmacological Prescription for Atrial Fibrillation, Dyslipidemia and Hypertension: Observational Analytical #TRIGERIA Study in Institutionalized Patients. Preprints 2023, 2023020202. https://doi.org/10.20944/preprints202302.0202.v1.
Cite as:
Esquirol Caussa, J.; Herrero Vila, E.; Sánchez Aldeguer, J. Pharmacological Prescription for Atrial Fibrillation, Dyslipidemia and Hypertension: Observational Analytical #TRIGERIA Study in Institutionalized Patients. Preprints2023, 2023020202. https://doi.org/10.20944/preprints202302.0202.v1.
Esquirol Caussa, J.; Herrero Vila, E.; Sánchez Aldeguer, J. Pharmacological Prescription for Atrial Fibrillation, Dyslipidemia and Hypertension: Observational Analytical #TRIGERIA Study in Institutionalized Patients. Preprints 2023, 2023020202. https://doi.org/10.20944/preprints202302.0202.v1.
Abstract
INTRODUCTION: Cardiovascular prevention is less effective than expected due to the concern about polymedication of professionals and the lack of adherence of patients. Polypills are presented as a possible solution, increasing therapeutic adherence in the medium or long term and improving therapeutic results compared to the administration of drugs separately: they increase effectiveness and Adherence of patients to primary and secondary cardiovascular prevention programs, without increasing the cost of the intervention. OBJECTIVES: Study #Trigeria: to specify the combined prevalence of Atrial Fibrillation, Dyslipidemia and Hypertension and analyze the pharmacological prescription for these pathologies and the possible indications and advantages that would have the prescription of a polypill for these risk factors.METHODS: Observational analytical study on the pathological history in elderly institutionalized in nursing homes and analysis of prescribed oral medication.RESULTS: 169 people analyzed (79.3% women) from 4 nursing homes; 8.9% had a history of Atrial Fibrillation, Dyslipidemia and Arterial Hypertension; these had a higher prevalence of heart disease (42.9%) and Cerebral Vascular Accident (35.7%). Polymedication was present in 88.5%, with an average of 6.94 oral drugs prescribed; among those with the three pathological antecedents, the average number of oral medications was 8.60. Only 26.7% of those with all three factors were prescribed drugs to control them.DISCUSSION: There are high rates of polymedication in the sample and low rates of prescription of antiplatelet agents in people with Atrial Fibrillation (26.5%); the low prescription of statins and antihypertensives of the ACE inhibitor or ARB-II groups may be due to good control with non-pharmacological measures or by the use of other groups of drugs . A polypill holding the drugs that control the three factors studied could increase the prescription rate while simplifying the administration schedule and reducing polymedication by 23.25% improving prescription, increasing adherence and control of risk factors without increasing pharmaceutical expenditure.CONCLUSIONS: There is a low rate of prescription of antiplatelet agents among people with atrial fibrillation. Combination methods (polypills) can increase the suitability of prescriptions in people with polypathology, improving prescribing, simplifying administration and increasing adherence to pharmacological treatments.
Keywords
Dyslipidemia; Atrial Fibrillation; Geriatrics; High Blood Pressure; Polymedication; Polypill
Subject
MEDICINE & PHARMACOLOGY, Cardiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
