Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Small RNA Profiling in HTLV-1-infected Patient with Acute Adult T-cell Leukemia-Lymphoma at Diagnosis and After Maintenance Therapy: A Case Study

Version 1 : Received: 13 January 2023 / Approved: 17 January 2023 / Online: 17 January 2023 (11:06:37 CET)

How to cite: Pessôa, R.; Souza, D.R.V.; Nukui, Y.; Pereira, J.; Penalva de Oliveira, A.C.; Casseb, J.; Duarte, A.J.D.S.; Sanabani, S.S. Small RNA Profiling in HTLV-1-infected Patient with Acute Adult T-cell Leukemia-Lymphoma at Diagnosis and After Maintenance Therapy: A Case Study. Preprints 2023, 2023010310. https://doi.org/10.20944/preprints202301.0310.v1 Pessôa, R.; Souza, D.R.V.; Nukui, Y.; Pereira, J.; Penalva de Oliveira, A.C.; Casseb, J.; Duarte, A.J.D.S.; Sanabani, S.S. Small RNA Profiling in HTLV-1-infected Patient with Acute Adult T-cell Leukemia-Lymphoma at Diagnosis and After Maintenance Therapy: A Case Study. Preprints 2023, 2023010310. https://doi.org/10.20944/preprints202301.0310.v1

Abstract

Small RNAs (sRNA) are epigenetic regulators of essential biological processes that have been linked to the onset and progression of leukemia, including acute adult T-cell leukemia-lymphoma (ATLL) caused by the retrovirus Human T-lymphotropic virus type 1. Here, we describe the sRNA profile of a 30-year-old female with ATLL at diagnosis and after maintenance therapy, with the goal of correlating their expression levels with response to therapy.

Keywords

small RNA; HTLV-1; ATLL; massive parallel sequencing

Subject

Medicine and Pharmacology, Oncology and Oncogenics

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.