Ayusso, L.L.; Girol, A.P.; Burdmann, E.A. Protective Effect of Green Tea (Camellia sinensis) against Kidney Diseases. Preprints2022, 2022120287. https://doi.org/10.20944/preprints202212.0287.v1
APA Style
Ayusso, L.L., Girol, A.P., & Burdmann, E.A. (2022). Protective Effect of Green Tea (<em>Camellia sinensis</em>) against Kidney Diseases. Preprints. https://doi.org/10.20944/preprints202212.0287.v1
Chicago/Turabian Style
Ayusso, L.L., Ana Paula Girol and Emmanuel A. Burdmann. 2022 "Protective Effect of Green Tea (<em>Camellia sinensis</em>) against Kidney Diseases" Preprints. https://doi.org/10.20944/preprints202212.0287.v1
Abstract
Kidney diseases are a global health problem, and their frequency is continuously increasing. Available treatments provide limited kidney protection. The protective effect of the green tea polyphenol epigallocatechin-3-gallate (EGCG) in several diseases have been extensively investigated. Experimental and clinical studies have shown that the antioxidant, anti-inflammatory, and anti-apoptotic properties of EGCG are promising for the treatment and/or prevention of kidney diseases. This review analyzes the available evidence on the effects, and the likely protective mechanisms of action, of EGCG in a broad spectrum of kidney diseases, including acute kidney injury, drug-induced nephrotoxicity, kidney stone disease, diabetic nephropathy, chronic kidney disease, and kidney fibrosis.
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