Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A Dual Primary Malignancy – Ewing Sarcoma and Prostate Adenocarcinoma in A Single Patient

Version 1 : Received: 20 November 2022 / Approved: 23 November 2022 / Online: 23 November 2022 (07:47:52 CET)

How to cite: Shpigelman, A.; Maman, D.; Bernfeld, B. A Dual Primary Malignancy – Ewing Sarcoma and Prostate Adenocarcinoma in A Single Patient. Preprints 2022, 2022110441. https://doi.org/10.20944/preprints202211.0441.v1 Shpigelman, A.; Maman, D.; Bernfeld, B. A Dual Primary Malignancy – Ewing Sarcoma and Prostate Adenocarcinoma in A Single Patient. Preprints 2022, 2022110441. https://doi.org/10.20944/preprints202211.0441.v1

Abstract

Introduction: A dual malignancy with both Ewing Sarcoma and Prostate Adenocarcinoma has not been reported in the English literature. We report a case of simultaneous diagnosis of Ewing sarcoma and prostate adenocarcinoma with profound clinical manifestation. Case presentation: A 53-year-old male with advanced metastatic prostate cancer (Gleason-9) admitted with classical presentation of cauda equina syndrome including incontinence, back pain, and paresis following bilateral nephrostomy insertion for the treatment of bilateral renal hy-dronephrosis. The patient was diagnosed with an epidural abscess at the level of L5-S1 and an emergency surgical spine decompression was performed. No abscess was found, and pathology results showed a concomitant primary Ewing sarcoma in the spine. Conclusions: Very rare occurrences of a dual primary malignancy, in this case, Ewing sarcoma and prostate adenocarcinoma, should be kept in mind in patients suffering from complex clinical course of malignancies.

Keywords

Ewing sarcoma; Prostate adenocarcinoma; Cauda equina syndrome; Dual primary malignancy.

Subject

Medicine and Pharmacology, Urology and Nephrology

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