Submitted:
11 November 2022
Posted:
14 November 2022
Read the latest preprint version here
Abstract
Aging kills 100,000 people a day - more than any other cause of death combined. The exact causes of aging have been much discussed, but the most pressing issue with regard to aging appears to me to be lipofuscin accumulation. That is, the accumulation of indigestible cellular garbage that needs to be removed from our cells, then the body. In this piece, I will explain why I think “getting rid of the garbage” should be at least one of our main goals with regard to longevity research for now.
Keywords:
Anti-aging therapy
; lipofuscin
; SENS
; oncolytic vector
; telomerase
; TFEB
; intracellular microbe
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