Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Gompertz Kinetics in Developmental Fields: An Information Theory Approach

Version 1 : Received: 17 August 2022 / Approved: 22 August 2022 / Online: 22 August 2022 (15:42:19 CEST)

How to cite: Baranowitz, S. Gompertz Kinetics in Developmental Fields: An Information Theory Approach. Preprints 2022, 2022080385. https://doi.org/10.20944/preprints202208.0385.v1 Baranowitz, S. Gompertz Kinetics in Developmental Fields: An Information Theory Approach. Preprints 2022, 2022080385. https://doi.org/10.20944/preprints202208.0385.v1

Abstract

A model for cell proliferation in developmental fields is derived from information theory using a few biological postulates. The model provides an explanation for the success of the Gompertz equation in describing the growth of embryonic, neoplastic, and regenerative systems. Although this equation has been applied to many growth phenomena, its use has been entirely empirical. A theoretical justification for the use of the Gompertz equation in characterizing developmental processes is presented. The model also accounts for a reported relationship among the parameters of the Gompertz equation. A method for quantification and comparison of the determination of developmental fields at different levels of organization is suggested.

Keywords

Developmental Field; Gompertz Equation; Information Theory; Developmental Biology

Subject

Biology and Life Sciences, Anatomy and Physiology

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