Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment

Filipa Lebre
,
Nivedita Chatterjee
ORCID logo ,
Samantha Costa
ORCID logo ,
Eli Fernández-de Gortari
,
Carla Lopes
ORCID logo ,
João Meneses
ORCID logo ,
Luís Ortiz
ORCID logo ,
Ana R. Ribeiro
ORCID logo ,
Vânia Vilas-Boas
,
Ernesto Alfaro-Moreno
* ORCID logo
Version 1 : Received: 14 May 2022 / Approved: 17 May 2022 / Online: 17 May 2022 (11:05:10 CEST)

A peer-reviewed article of this Preprint also exists.

Lebre, F.; Chatterjee, N.; Costa, S.; Fernández-de-Gortari, E.; Lopes, C.; Meneses, J.; Ortiz, L.; Ribeiro, A.R.; Vilas-Boas, V.; Alfaro-Moreno, E. Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment. Nanomaterials 2022, 12, 1810. Lebre, F.; Chatterjee, N.; Costa, S.; Fernández-de-Gortari, E.; Lopes, C.; Meneses, J.; Ortiz, L.; Ribeiro, A.R.; Vilas-Boas, V.; Alfaro-Moreno, E. Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment. Nanomaterials 2022, 12, 1810.

Abstract

The use of nanomaterials has been increasing in recent times, and they are widely used in industries such as cosmetics, drug, food, water treatment and agriculture. The rapid development of new nanomaterials demands a set of approaches to evaluate the potential toxicity and risks related to them. In this regard, nanosafety has been using and adapting already existing methods (toxicological approach), but the unique characteristics of nanomaterials demand new approaches (nanotoxicology) to fully understand the potential toxicity, immunotoxicity and (epi)genotoxicity. Also, new technologies, such as organ-on-chip and sophisticated sensors, are under development and/or adaptation. All the information generated is used to develop new in silico approaches trying to predict the potential effects of newly developed materials. The overall evaluation of how from the production to final disposition chain of nanomaterials is evaluated under Life Cycle Assessment (LCA), which is becoming an important element of nanosafety considering sustainability and environmental impact. In this review we give an overview of all these elements of nanosafety.

Keywords

Nanomaterials; Nanotoxicology; Immunotoxicity; Genotoxicity; Epigenetics; Advanced in vitro models; In silico; Life Cycle Assessment

Subject

Chemistry and Materials Science, Nanotechnology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF Download Supplementary

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Supplementary Files Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.