Version 1
: Received: 16 May 2022 / Approved: 16 May 2022 / Online: 16 May 2022 (08:12:52 CEST)
How to cite:
Tamagawa, H.; Nakahata, T.; Sugimori, R.; Delalande, B. The Membrane Potential Has a Primary Key Equation. Preprints2022, 2022050200. https://doi.org/10.20944/preprints202205.0200.v1
Tamagawa, H.; Nakahata, T.; Sugimori, R.; Delalande, B. The Membrane Potential Has a Primary Key Equation. Preprints 2022, 2022050200. https://doi.org/10.20944/preprints202205.0200.v1
Tamagawa, H.; Nakahata, T.; Sugimori, R.; Delalande, B. The Membrane Potential Has a Primary Key Equation. Preprints2022, 2022050200. https://doi.org/10.20944/preprints202205.0200.v1
APA Style
Tamagawa, H., Nakahata, T., Sugimori, R., & Delalande, B. (2022). The Membrane Potential Has a Primary Key Equation. Preprints. https://doi.org/10.20944/preprints202205.0200.v1
Chicago/Turabian Style
Tamagawa, H., Ren Sugimori and Bernard Delalande. 2022 "The Membrane Potential Has a Primary Key Equation" Preprints. https://doi.org/10.20944/preprints202205.0200.v1
Abstract
Although there is a common physiological notion that the origin of the membrane potential is attributed to transmembrane ion transport, it is theoretically possible to explain its generation by the mechanism of ion adsorption. It was previously suggested that the ion adsorption mechanism led even to the potential formulas which are even identical to either the famous Nernst equation or Goldman-Hodgkin-Katz equation. Our further analysis shown in this paper indicates that the potential formula based on the ion adsorption mechanism leads to one equation which is the function of material surface charge density and the material surface potential. Furthermore, we confirmed that the equation holds in all the different experimental systems we studied. Although we have not succeeded in elucidating why such an equation is established, the equation appears to be the key equation governing the characteristics of the membrane potential regardless of the systems in question.
Keywords
membrane potential; Nernst equation; ion adsorption; surface charge; surface potential
Subject
Biology and Life Sciences, Biophysics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
