Version 1
: Received: 1 May 2022 / Approved: 4 May 2022 / Online: 4 May 2022 (14:17:42 CEST)
Version 2
: Received: 21 May 2022 / Approved: 23 May 2022 / Online: 23 May 2022 (11:00:06 CEST)
How to cite:
Roy, B.; Runa, S. A. COVID-19 and Diabetes: Pathophysiological Mechanism of Multi-System Organ Failure. Preprints2022, 2022050014. https://doi.org/10.20944/preprints202205.0014.v1
Roy, B.; Runa, S. A. COVID-19 and Diabetes: Pathophysiological Mechanism of Multi-System Organ Failure. Preprints 2022, 2022050014. https://doi.org/10.20944/preprints202205.0014.v1
Roy, B.; Runa, S. A. COVID-19 and Diabetes: Pathophysiological Mechanism of Multi-System Organ Failure. Preprints2022, 2022050014. https://doi.org/10.20944/preprints202205.0014.v1
APA Style
Roy, B., & Runa, S. A. (2022). COVID-19 and Diabetes: Pathophysiological Mechanism of Multi-System Organ Failure. Preprints. https://doi.org/10.20944/preprints202205.0014.v1
Chicago/Turabian Style
Roy, B. and Sadia Afrin Runa. 2022 "COVID-19 and Diabetes: Pathophysiological Mechanism of Multi-System Organ Failure" Preprints. https://doi.org/10.20944/preprints202205.0014.v1
Abstract
Since the discovery of the Coronavirus disease 2019 (COVID-19) outbreak, a vast majority of studies have been carried out that confirmed the worst outcome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in people with preexisting health conditions, including diabetes. Both diabetes and SARS-CoV-2 have their independent ability to induce the pathogenesis of multi-system organ dysfunction, while the co-existence of these two culprits can accelerate the pathophysiology and magnify the severity of the diseases. However, the exact pathophysiology of multi-system organ failure in diabetic patients after SARS-CoV-2 infection is still obscure. This review summarized the organ-specific possible molecular mechanisms of SARS-CoV-2 and diabetes-induced pathophysiology of several diseases, including the lungs, heart, kidney, brain, eyes, gastrointestinal system, and bones and subsequent manifestation of multi-system organ failure.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
