Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Robust PVC Identification by Fusing Expert System and Deep Learning

Version 1 : Received: 27 February 2022 / Approved: 3 March 2022 / Online: 3 March 2022 (07:22:36 CET)

A peer-reviewed article of this Preprint also exists.

Cai, Z.; Wang, T.; Shen, Y.; Xing, Y.; Yan, R.; Li, J.; Liu, C. Robust PVC Identification by Fusing Expert System and Deep Learning. Biosensors 2022, 12, 185. Cai, Z.; Wang, T.; Shen, Y.; Xing, Y.; Yan, R.; Li, J.; Liu, C. Robust PVC Identification by Fusing Expert System and Deep Learning. Biosensors 2022, 12, 185.

Abstract

Premature ventricular contraction (PVC) is one of the common ventricular arrhythmias, which may cause stroke or sudden cardiac death. Automatic long-term electrocardiogram (ECG) analysis algorithms could provide diagnosis suggestion even early warning for physicians, however, they are mutually-exclusive in terms of robustness, generalization and low complexity. In this study, a novel PVC recognition algorithm that combines deep learning-based heartbeat template clusterer and expert system-based heartbeat classifier is proposed. Long short-term memory-based auto-encoder (LSTM-AE) network was used to extract features from ECG heartbeats for K-means clustering. Thus, the templates were constructed and determined based on clustering results. Finally, the PVC heartbeats were recognized based on a combination of multiple rules, including template matching and rhythm characteristics. Three quantitative parameters, sensitivity (Se), positive predictive value (P+) and accuracy (ACC), were used to evaluate the performances of the proposed method on the MIT-BIH Arrhythmia database and the St. Petersburg Institute of Cardiological Technics database. Se on the two test databases was 87.51% and 87.92%, respectively; P+ was 92.47% and 93.18%, respectively; and ACC was 98.63% and 97.89%, respectively. The PVC scores on the 3rd China Physiological Signal Challenge 2020 training set and hidden test set were 36,256 and 46,706, respectively, which could rank first in the open-source codes. The results showed that the combination strategy of expert system and deep learning can provide new insights for robust and generalized PVC identification from long-term single-lead ECG recordings.

Keywords

electrocardiogram; K-means clustering algorithm; premature ventricular contraction; rule-based decision algorithm

Subject

Engineering, Bioengineering

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