Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Phage Therapy: A Potential Novel Therapeutic Treatment of Methicillin-Resistant Staphylococcus aureus

Version 1 : Received: 21 November 2021 / Approved: 22 November 2021 / Online: 22 November 2021 (13:54:16 CET)

How to cite: Gildea, L.; Ayariga, J.; Abugri, J.; Villafane, R. Phage Therapy: A Potential Novel Therapeutic Treatment of Methicillin-Resistant Staphylococcus aureus. Preprints 2021, 2021110397 (doi: 10.20944/preprints202111.0397.v1). Gildea, L.; Ayariga, J.; Abugri, J.; Villafane, R. Phage Therapy: A Potential Novel Therapeutic Treatment of Methicillin-Resistant Staphylococcus aureus. Preprints 2021, 2021110397 (doi: 10.20944/preprints202111.0397.v1).

Abstract

The emergence of multidrug-resistant bacterial strains, especially in the clinical setting, has renewed interest in alternative treatment methods. The utilization of prokaryotic viruses in phage therapy has demonstrated potential as a novel treatment method against multidrug-resistant bacterial infections. As the post-antibiotic era quickly approaches, the development and standardization of phage therapy is critically relevant to public health. This review serves to highlight the development of phage therapy against methicillin-resistant Staphylococcus aureus (MRSA), an antibiotic-resistant bacterial strain responsible for severe clinical infections.

Keywords

Bacteriophage therapy; MRSA; antibiotic resistance; virulence factors

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