Precision Public Health Through Serological Biomarkers: An Integrated Surveillance Platform to Inform Public Health Interventions

Kirsten E. Wiens; Barbara Jauregui; Benjamin F. Arnold; Kathryn Banke; Djibril Wade; Kyla Hayford; Adriana Costero-Saint Denis; Robert H. Hall; Henrik Salje; Isabel Rodriguez-Barraquer; Andrew S. Azman; Guy Vernet; Daniel T. Leung

doi:10.20944/preprints202110.0444.v1

How to cite: Wiens, K.E.; Jauregui, B.; Arnold, B.F.; Banke, K.; Wade, D.; Hayford, K.; Costero-Saint Denis, A.; Hall, R.H.; Salje, H.; Rodriguez-Barraquer, I.; Azman, A.S.; Vernet, G.; Leung, D.T. Precision Public Health Through Serological Biomarkers: An Integrated Surveillance Platform to Inform Public Health Interventions. Preprints 2021, 2021100444. https://doi.org/10.20944/preprints202110.0444.v1 Wiens, K.E.; Jauregui, B.; Arnold, B.F.; Banke, K.; Wade, D.; Hayford, K.; Costero-Saint Denis, A.; Hall, R.H.; Salje, H.; Rodriguez-Barraquer, I.; Azman, A.S.; Vernet, G.; Leung, D.T. Precision Public Health Through Serological Biomarkers: An Integrated Surveillance Platform to Inform Public Health Interventions. Preprints 2021, 2021100444. https://doi.org/10.20944/preprints202110.0444.v1

Abstract

The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 20 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group’s insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.

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Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Precision Public Health Through Serological Biomarkers: An Integrated Surveillance Platform to Inform Public Health Interventions

Abstract

Keywords

Subject

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