Expanding Interactome Analyses beyond Model Eukaryotes

Katherine James; Anil Wipat; Simon Cockell

doi:10.20944/preprints202110.0185.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 8 October 2021 / Approved: 12 October 2021 / Online: 12 October 2021 (14:24:56 CEST)

Interactome analyses have traditionally been applied to yeast, human and other model organisms due to the availability of protein-protein interactions data for these species. Recently these techniques have been applied to more diverse species using computational interaction prediction from genome sequence and other data types. This review describes the various types of computational interactome networks that can be created and how they have been used in diverse eukaryotic species, highlighting some of the key interactome studies in non-model organisms.

systems biology; integrative bioinformatics; interactomics; eukaryotes; non-models; network biology

Computer Science and Mathematics, Mathematical and Computational Biology

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Expanding Interactome Analyses beyond Model Eukaryotes

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