Simakov, S.; Gamilov, T.; Liang, F.; Kopylov, P. Computational Analysis of Haemodynamic Indices in Synthetic Atherosclerotic Coronary Netwroks. Mathematics2021, 9, 2221.
Simakov, S.; Gamilov, T.; Liang, F.; Kopylov, P. Computational Analysis of Haemodynamic Indices in Synthetic Atherosclerotic Coronary Netwroks. Mathematics 2021, 9, 2221.
Simakov, S.; Gamilov, T.; Liang, F.; Kopylov, P. Computational Analysis of Haemodynamic Indices in Synthetic Atherosclerotic Coronary Netwroks. Mathematics2021, 9, 2221.
Simakov, S.; Gamilov, T.; Liang, F.; Kopylov, P. Computational Analysis of Haemodynamic Indices in Synthetic Atherosclerotic Coronary Netwroks. Mathematics 2021, 9, 2221.
Abstract
Haemodynamic indices are widely used in clinical practice for deciding on a particular type of treatment. Low quality of the CT data and tachycardia complicate interpretation of the measured or simulated values. In this work, we present a novel approach for evaluating resistances in terminal coronary arteries. Using 14 measurements from 10 patients, we show that this algorithm retains the accuracy of 1D haemodynamic simulations in less detailed (truncated) geometric models of coronary networks. We also apply the variable systole fraction model to study the effect of elevated heart rate on the values of FFR, CFR and iFR. We conclude that tachycardia may produce both overestimation or underestimation of coronary stenosis significance.
Computer Science and Mathematics, Algebra and Number Theory
Copyright:
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