Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Middle Ear Packing and External Ear Packing with Fibrin Glue Enhances the Success of Fat Myringoplasty without Hyaluronic Acid Disc

Version 1 : Received: 29 July 2021 / Approved: 30 July 2021 / Online: 30 July 2021 (13:25:54 CEST)

A peer-reviewed article of this Preprint also exists.

KIM, J.; PARK, H.-J.; LEE, D.-N.; JANG, C.H. Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc. In Vivo 2021, 36, 490–495, doi:10.21873/invivo.12729. KIM, J.; PARK, H.-J.; LEE, D.-N.; JANG, C.H. Middle Ear Packing and External Ear Packing With Fibrin Glue Enhance the Success of Fat Myringoplasty Without Hyaluronic Acid Disc. In Vivo 2021, 36, 490–495, doi:10.21873/invivo.12729.

Abstract

Background: To date, FM using middle ear packing has rarely reported. In this study, we hypothesized that middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of TMP closure regardless of perforation size. Methods: Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at tertiary referral center were encountered and analyzed. The success rate and audiologic outcome was analyzed. Results: The mean successful TM closure rate was 88.0 %. The success rate by different age generation was not significant difference. The size of the perforation grade showed no significant difference. The perforation site by anterior or posterior was not significant. The preoperative mean threshold of AC, BC and ABG were 55.71, 12.98 and 42.73 dB respectively. The postoperative mean threshold of AC, BC and ABG were 23.67, 12.98 and 10.69 dB. The change of preoperative and postoperative hearing showed statistically significant. Conclusion: From our results, the simple trimming of the perforation edge and middle ear packing with external ear canal packing using fibrin glue induced the stable adhesion between the remnant TM and the fat graft.

Keywords

tympanic membrane; chronic perforation; fat myringoplasty; success rate; middle ear packing; fibrin glue packing

Subject

Medicine and Pharmacology, Immunology and Allergy

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