Working Paper Review Version 1 This version is not peer-reviewed

New Insights in the Biology of the Emerging Tembusu Virus

Version 1 : Received: 7 July 2021 / Approved: 9 July 2021 / Online: 9 July 2021 (07:36:16 CEST)

A peer-reviewed article of this Preprint also exists.

Hamel, R.; Phanitchat, T.; Wichit, S.; Morales Vargas, R.E.; Jaroenpool, J.; Diagne, C.T.; Pompon, J.; Missé, D. New Insights into the Biology of the Emerging Tembusu Virus. Pathogens 2021, 10, 1010. Hamel, R.; Phanitchat, T.; Wichit, S.; Morales Vargas, R.E.; Jaroenpool, J.; Diagne, C.T.; Pompon, J.; Missé, D. New Insights into the Biology of the Emerging Tembusu Virus. Pathogens 2021, 10, 1010.

Abstract

Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained for a long time in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccine and therapeutic with a particular focus on host-virus interaction.

Keywords

TMUV; emergent arboviruses; zoonosis; host-pathogen interactions; vector

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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