Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Bioinformatics Approaches for Determining the Functional Impact of Repetitive Elements on Non-coding RNAs

Version 1 : Received: 4 June 2021 / Approved: 4 June 2021 / Online: 4 June 2021 (15:33:17 CEST)

How to cite: Zeng, C.; Takeda, A.; Sekine, K.; Osato, N.; Fukunaga, T.; Hamada, M. Bioinformatics Approaches for Determining the Functional Impact of Repetitive Elements on Non-coding RNAs. Preprints 2021, 2021060145 (doi: 10.20944/preprints202106.0145.v1). Zeng, C.; Takeda, A.; Sekine, K.; Osato, N.; Fukunaga, T.; Hamada, M. Bioinformatics Approaches for Determining the Functional Impact of Repetitive Elements on Non-coding RNAs. Preprints 2021, 2021060145 (doi: 10.20944/preprints202106.0145.v1).

Abstract

With a large number of annotated non-coding RNAs (ncRNAs), repetitive sequences are found to constitute functional components (termed as repetitive elements) in ncRNAs that perform specific biological functions. Bioinformatics analysis is a powerful tool for improving our understanding of the role of repetitive elements in ncRNAs. This chapter summarizes recent findings that reveal the role of repetitive elements in ncRNAs. Furthermore, relevant bioinformatics approaches are systematically reviewed, which promises to provide valuable resources for studying the functional impact of repetitive elements on ncRNAs.

Subject Areas

Repetitive element; Transposable element; Non-coding RNA; ncRNA; Functional element; Bioinformatics

Comments (2)

Comment 1
Received: 7 June 2021
Commenter: Alexandre Paschoal
The commenter has declared there is no conflict of interests.
Comment: Congratulations on the manuscript. To help, May I suggest to include to include these to databases related to your text:

PlaNC-TE
https://doi.org/10.1093/database/bay078 http://planc-te.cp.utfpr.edu.br/

and

PlanTE-MIR DB
https://doi.org/10.1007/s10142-016-0480-5 http://bioinfo-tool.cp.utfpr.edu.br/plantemirdb/
+ Respond to this comment
Response 1 to Comment 1
Received: 8 June 2021
Commenter: Chao Zeng
The commenter has declared there is no conflict of interests.
Comment: Thank you for contacting us. As I mentioned in the responding e-mail, we will consider adding these two databases to our manuscript before publication.

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