Version 1
: Received: 31 May 2021 / Approved: 1 June 2021 / Online: 1 June 2021 (09:44:47 CEST)
How to cite:
Wong-Chew, R.M.; Cabrera, E.X.R.; Valdez, C.A.R.; Gascon, J.L.; Juárez, L.M.; de la Cerda, M.L.R.; Romero, A.R.V.; Fernández, S.A.; Fernández, M.S.; Bello, H.H.; Castañeda, L.M.; Avendaño, M.A.; Cruz, J.A.H.; Martínez, N.Á.; Contreras, L.F.; de la Cerda, L.R.G.; Flores, A.J.; Martínez-Juarez, L.A.; Álvarez-Hernández, D.; Gallardo-Rincón, H.; Dolci, G.F.; Tapia-Conyer, R.; Vazquez, R.R.V. Symptom Cluster Analysis of long COVID-19 in Patients Discharged from the Temporary COVID-19 Hospital in Mexico City: A Longitudinal Study. Preprints2021, 2021060011. https://doi.org/10.20944/preprints202106.0011.v1.
Wong-Chew, R.M.; Cabrera, E.X.R.; Valdez, C.A.R.; Gascon, J.L.; Juárez, L.M.; de la Cerda, M.L.R.; Romero, A.R.V.; Fernández, S.A.; Fernández, M.S.; Bello, H.H.; Castañeda, L.M.; Avendaño, M.A.; Cruz, J.A.H.; Martínez, N.Á.; Contreras, L.F.; de la Cerda, L.R.G.; Flores, A.J.; Martínez-Juarez, L.A.; Álvarez-Hernández, D.; Gallardo-Rincón, H.; Dolci, G.F.; Tapia-Conyer, R.; Vazquez, R.R.V. Symptom Cluster Analysis of long COVID-19 in Patients Discharged from the Temporary COVID-19 Hospital in Mexico City: A Longitudinal Study. Preprints 2021, 2021060011. https://doi.org/10.20944/preprints202106.0011.v1.
Cite as:
Wong-Chew, R.M.; Cabrera, E.X.R.; Valdez, C.A.R.; Gascon, J.L.; Juárez, L.M.; de la Cerda, M.L.R.; Romero, A.R.V.; Fernández, S.A.; Fernández, M.S.; Bello, H.H.; Castañeda, L.M.; Avendaño, M.A.; Cruz, J.A.H.; Martínez, N.Á.; Contreras, L.F.; de la Cerda, L.R.G.; Flores, A.J.; Martínez-Juarez, L.A.; Álvarez-Hernández, D.; Gallardo-Rincón, H.; Dolci, G.F.; Tapia-Conyer, R.; Vazquez, R.R.V. Symptom Cluster Analysis of long COVID-19 in Patients Discharged from the Temporary COVID-19 Hospital in Mexico City: A Longitudinal Study. Preprints2021, 2021060011. https://doi.org/10.20944/preprints202106.0011.v1.
Wong-Chew, R.M.; Cabrera, E.X.R.; Valdez, C.A.R.; Gascon, J.L.; Juárez, L.M.; de la Cerda, M.L.R.; Romero, A.R.V.; Fernández, S.A.; Fernández, M.S.; Bello, H.H.; Castañeda, L.M.; Avendaño, M.A.; Cruz, J.A.H.; Martínez, N.Á.; Contreras, L.F.; de la Cerda, L.R.G.; Flores, A.J.; Martínez-Juarez, L.A.; Álvarez-Hernández, D.; Gallardo-Rincón, H.; Dolci, G.F.; Tapia-Conyer, R.; Vazquez, R.R.V. Symptom Cluster Analysis of long COVID-19 in Patients Discharged from the Temporary COVID-19 Hospital in Mexico City: A Longitudinal Study. Preprints 2021, 2021060011. https://doi.org/10.20944/preprints202106.0011.v1.
Abstract
Recently, several reports have emerged describing the long-term consequences of COVID-19 that may affect multiple systems, suggesting its chronicity. As further research is needed, we conducted a longitudinal observational study to report the prevalence and associated risk factors of long-term health consequences of COVID-19 by symptom clusters in patients discharged from the Temporary COVID-19 Hospital (TCH) in Mexico City. Self-reported clinical symptom data were collected via telephone calls over 90 days post-discharge. Among 4670 patients discharged from the TCH, we identified 45 symptoms across eight symptom clusters (neurological; mood disorders; systemic; respiratory; musculoskeletal; ear, nose, and throat; dermatological; and gastrointestinal). We observed that the neurological, dermatological, and mood disorder symptom clusters persisted in >30% of patients at 90 days post-discharge. Although most symptoms decreased in frequency between day 30 and 90, alopecia and the dermatological symptom cluster significantly increased (p<0·00001). Women were more prone than men to develop long-term symptoms and invasive mechanical ventilation also increased the frequency of symptoms at 30-days post-discharge. Overall, we observed that symptoms often persisted regardless of disease severity. We hope these findings will help promote public health strategies that ensure equity in the access to solutions focused on the long-term consequences of COVID-19.
Keywords
long covid; symptom cluster; persistent symptoms; long-term; Mexico; survey
Subject
LIFE SCIENCES, Biochemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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