Version 1
: Received: 13 April 2021 / Approved: 14 April 2021 / Online: 14 April 2021 (11:40:14 CEST)
How to cite:
Nagasawa, H.T.; Crankshaw, D.L.; Briggs, J.E.; Vince, R. An Orally Bioavailable (Mice) Prodrug of Glutathione. Preprints2021, 2021040368. https://doi.org/10.20944/preprints202104.0368.v1
Nagasawa, H.T.; Crankshaw, D.L.; Briggs, J.E.; Vince, R. An Orally Bioavailable (Mice) Prodrug of Glutathione. Preprints 2021, 2021040368. https://doi.org/10.20944/preprints202104.0368.v1
Nagasawa, H.T.; Crankshaw, D.L.; Briggs, J.E.; Vince, R. An Orally Bioavailable (Mice) Prodrug of Glutathione. Preprints2021, 2021040368. https://doi.org/10.20944/preprints202104.0368.v1
APA Style
Nagasawa, H.T., Crankshaw, D.L., Briggs, J.E., & Vince, R. (2021). An Orally Bioavailable (Mice) Prodrug of Glutathione. Preprints. https://doi.org/10.20944/preprints202104.0368.v1
Chicago/Turabian Style
Nagasawa, H.T., Jacquie E. Briggs and Robert Vince. 2021 "An Orally Bioavailable (Mice) Prodrug of Glutathione" Preprints. https://doi.org/10.20944/preprints202104.0368.v1
Abstract
Cysteine-glutathione mixed disulfide (CySSG), a prodrug of glutathione (GSH) --the “Master Antioxidant”, was found to be orally bioavailable in mice, and protected against a toxic dose of acetaminophen. If oral bioavailability can also be demonstrated in humans, this suggests a wide range of applicability for CySSG.
Keywords
CySSG; prodrug; glutathione; orally; bioavailable
Subject
Chemistry and Materials Science, Medicinal Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
