Preprint Brief Report Version 1 Preserved in Portico This version is not peer-reviewed

SARS-CoV-2 Spike and Telomerase RNAs Compared to Arrive at an Explanation for Increased Ageing in Alveolar Cells in Severe COVID-19

Version 1 : Received: 21 March 2021 / Approved: 22 March 2021 / Online: 22 March 2021 (15:48:20 CET)

How to cite: Geurdes, H. SARS-CoV-2 Spike and Telomerase RNAs Compared to Arrive at an Explanation for Increased Ageing in Alveolar Cells in Severe COVID-19. Preprints 2021, 2021030551 (doi: 10.20944/preprints202103.0551.v1). Geurdes, H. SARS-CoV-2 Spike and Telomerase RNAs Compared to Arrive at an Explanation for Increased Ageing in Alveolar Cells in Severe COVID-19. Preprints 2021, 2021030551 (doi: 10.20944/preprints202103.0551.v1).

Abstract

In this letter we investigate if SARS-CoV-2 RNA is involved in the increased ageing of alveolar cells. Our in silico study is explorative. With the results we are able to outline experiments with AEC2 repair of bleomycin damaged alveolar cells. If AEC2 repair capability is diminished by spike RNA then perhaps this result provides a first step on a route to treat immortal lung cancer cells.

Subject Areas

Telomere attrition in covid19; telomerase and spike RNA

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