Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Flavonoids in Lemon and Grapefruit IntegroPectin

Version 1 : Received: 24 February 2021 / Approved: 26 February 2021 / Online: 26 February 2021 (13:47:16 CET)

How to cite: Scurria, A.; Sciortino, M.; Albanese, L.; Nuzzo, D.; Zabini, F.; Meneguzzo, F.; Alduina, R.V.; Presentato, A.; Pagliaro, M.; Avellone, G.; Ciriminna, R. Flavonoids in Lemon and Grapefruit IntegroPectin. Preprints 2021, 2021020620 (doi: 10.20944/preprints202102.0620.v1). Scurria, A.; Sciortino, M.; Albanese, L.; Nuzzo, D.; Zabini, F.; Meneguzzo, F.; Alduina, R.V.; Presentato, A.; Pagliaro, M.; Avellone, G.; Ciriminna, R. Flavonoids in Lemon and Grapefruit IntegroPectin. Preprints 2021, 2021020620 (doi: 10.20944/preprints202102.0620.v1).

Abstract

Following the analysis of terpenes present in new lemon and grapefruit “IntegroPectin” pectins obtained via the hydrodynamic cavitation of industrial lemon and grapefruit processing waste, the HPLC-MS analysis of the flavonoid compounds reveals the presence of eriocitrin, naringin, hesperidin and kaempferol typical of the respective citrus fruits. The pectic fibers rich in rhamnogalacturonan-I “hairy” regions act as chemical sponges adsorbing and concentrating at their outer surface highly bioactive citrus flavonoids and terpenes. These findings, together with the unique molecular structure of these new whole citrus pectins, provide preliminary insight into the broad-scope and powerful biological activity of these biomaterials. Numerous new biomedical applications beyond prevention and treatment of microbial infections and neurodegenerative disease are anticipated.

Keywords

IntegroPectin, naringin, eriocitrin, citrus, flavonoids, pectin, circular economy

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