Study of Essential Sequence Analysis Tools in Bioinformatics : A Brief Overview

Ghafran Ali; Kanza Ashfaq

doi:10.20944/preprints202101.0135.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 6 January 2021 / Approved: 8 January 2021 / Online: 8 January 2021 (10:30:03 CET)

Sequence analysis program is outlined that analyzes and investigates homology between various nucleic acid or protein sequence. The dot matrix technique compares the sequences and the consensus sequence is obtained by superimposing on each other all the dot matrices. Local Alignment and Global Alignment both sequence from start to end is the best possible alignment over the entire duration between the two sequences. This method is more important to align with two closely related sequences roughly the same length. This method may not able to generate optimal results for divergent sequences and variable length sequence because between the two sequences it does not recognize very similar local region.

Global Alignment; Local Alignment; Heuristic Algorithm; Exhaustive Algorithm

Biology and Life Sciences, Biochemistry and Molecular Biology

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Study of Essential Sequence Analysis Tools in Bioinformatics : A Brief Overview

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