Preprint Concept Paper Version 1 Preserved in Portico This version is not peer-reviewed

Can Manipulation of Soil Microbiota Enhance, Stabilize and Sustain Cannabinoid Production?

Version 1 : Received: 28 December 2020 / Approved: 29 December 2020 / Online: 29 December 2020 (15:48:00 CET)

A peer-reviewed article of this Preprint also exists.

Journal reference: Journal of Cannabis Research 2021, 3
DOI: 10.1186/s42238-021-00082-0


Cannabis is one of the oldest cultivated crops in the history for food, fiber and drugs for thousands of years. Extension of cannabis genetic variation developed in a wide- ranging choice of varieties with various complementary phenotypes and secondary metabolites. Cannabis grow practices is very diverse, especially indoor cultivation factors, such as different lighting conditions, pot size, humidity, fertilizers. These growth factors influence a lot on the production of cannabinoids. For medical or pharmaceutical purposes, ratio of CBD or THC is very important. Plants traits and metabolic compounds are related to various conditions produced by microbes. Investigating this crosstalk between plants and microbes can play a vital role not only for stimulating the biosynthetic and signaling pathways of the host plants for the production of agronomically or pharmaceutically essential metabolic compounds but also against pathogens. This study emphasis on decoding the crosstalk between cannabis and associated microbes in the belowground environmental niches that would unravel the complexity of stabilizing cannabinoid production.


cannabis; microbiota; cannabinoid


BIOLOGY, Anatomy & Morphology

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