Version 1
: Received: 18 December 2020 / Approved: 23 December 2020 / Online: 23 December 2020 (15:58:38 CET)
How to cite:
Baranowitz, S.; Nrekaj, M. Treatment of Covid-19 with Minocycline and a Guanosine-Restricted Diet: Case Report. Preprints2020, 2020120596. https://doi.org/10.20944/preprints202012.0596.v1
Baranowitz, S.; Nrekaj, M. Treatment of Covid-19 with Minocycline and a Guanosine-Restricted Diet: Case Report. Preprints 2020, 2020120596. https://doi.org/10.20944/preprints202012.0596.v1
Baranowitz, S.; Nrekaj, M. Treatment of Covid-19 with Minocycline and a Guanosine-Restricted Diet: Case Report. Preprints2020, 2020120596. https://doi.org/10.20944/preprints202012.0596.v1
APA Style
Baranowitz, S., & Nrekaj, M. (2020). Treatment of Covid-19 with Minocycline and a Guanosine-Restricted Diet: Case Report. Preprints. https://doi.org/10.20944/preprints202012.0596.v1
Chicago/Turabian Style
Baranowitz, S. and Marie Nrekaj. 2020 "Treatment of Covid-19 with Minocycline and a Guanosine-Restricted Diet: Case Report" Preprints. https://doi.org/10.20944/preprints202012.0596.v1
Abstract
We report the treatment of a 21-year-old female Covid-19 patient by a novel combination of minocycline and a guanosine-restricted diet. Minocycline is an antibiotic with well documented broad spectrum anti-viral effects, including evidence of activity against SARS-CoV-2. Deprivation of guanosine has been documented as an effective anti-viral modality in vitro and in animal models, and specific in vitro activity against CoV-SARS-2 has been reported. The patient's symptoms resolved rapidly.
Keywords
Covid-19, SARS-CoV-2, drug repurposing
Subject
Medicine and Pharmacology, Immunology and Allergy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
