Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Analysis for Disease Stages of Gait in Patients with Parkinson´s Disease

Version 1 : Received: 14 December 2020 / Approved: 15 December 2020 / Online: 15 December 2020 (12:39:34 CET)

A peer-reviewed article of this Preprint also exists.

Vila, M.H.; Pérez, R.; Mollinedo, I.; Cancela, J.M. Analysis of Gait for Disease Stage in Patients with Parkinson’s Disease. Int. J. Environ. Res. Public Health 2021, 18, 720. Vila, M.H.; Pérez, R.; Mollinedo, I.; Cancela, J.M. Analysis of Gait for Disease Stage in Patients with Parkinson’s Disease. Int. J. Environ. Res. Public Health 2021, 18, 720.

Abstract

Understanding the motor patterns underlying the movement of people with Parkinson's disease (PD) is fundamental to the effective targeting of non-pharmacological therapies. This study aims to analyze the gait pattern in relation to the evolutionary stage between I-II and III-IV according to the Hoehn and Yahr scale (H&Y) in people affected by PD. The study was conducted with the participation of 37 PD patients, with a mean age of 70.09±9.53 years, and of whom 48.64% were women. The inclusion criteria were: 1. To be diagnosed with PD; 2. To be in an evolutionary stage of the disease of between I and IV and; 3. To be able to walk independently and without any assistance. Kinematic and spatial-temporal parameters of the gait were analyzed. The results show differences in speed of movement, cadence, stride length, support duration, swing duration, step width, walking cycle duration and double support time between the stages analyzed. These results confirm the differences in PD gait pattern between stages I-II and III-IV. Different behaviors of the same variable were recorded depending on whether the right or left sides were affected by PD.

Keywords

locomotion disorder; cadence; gait oscillation; speed of movement; neurodegenerative disease

Subject

Medicine and Pharmacology, Immunology and Allergy

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