Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Pilot Study of Electronic Nicotine Delivery Systems (ENDS) Cessation Methods

Version 1 : Received: 5 December 2020 / Approved: 9 December 2020 / Online: 9 December 2020 (15:56:46 CET)

A peer-reviewed article of this Preprint also exists.

Sahr, M.; Kelsh, S.; Blower, N.; Sohn, M. Pilot Study of Electronic Nicotine Delivery Systems (ENDS) Cessation Methods. Pharmacy 2021, 9, 21. Sahr, M.; Kelsh, S.; Blower, N.; Sohn, M. Pilot Study of Electronic Nicotine Delivery Systems (ENDS) Cessation Methods. Pharmacy 2021, 9, 21.

Abstract

Currently 7.6% of the U.S. young adults aged 18-24 years old currently use e-cigarettes. This study piloted three methods of ENDS cessation by measuring cessation rates, motivational techniques that contributed to cessation success, and participants’ changes after decreasing vape use. Participants were randomized into three study arms [nicotine replacement therapy (NRT) + behavioral support, vape-taper + behavioral support, self-guided] in a 1:1:1 ratio. All participants were invited to attend 9 in-person or phone appointments over the 6 month study period. At 12 weeks, 3 of 7 (42.9%) participants in the NRT + behavioral support arm, 6 of 8 (75%) vape-taper + behavioral support arm, and 7 of 9 (77.8%) self-guided arm self-reported being vape- and nicotine-free. At 6 months, 3 of 7 (42.9%) participants in the NRT + behavioral support arm, 6 of 8 (75%) vape-taper + behavioral support arm, 4 of 9 (44.4%) self-guided arm self-reported being vape- and nicotine-free. A challenge to quitting and remain quit is social pressures, but participants identified self-control and establishing new habits to be the best methods to overcome the desire to vape. Participants who received behavioral support and a vape-taper plan from pharmacists were more likely to be vape- and nicotine-free at 6 months.

Keywords

electronic nicotine delivery systems; nicotine addiction; vaping; cessation

Subject

Medicine and Pharmacology, Immunology and Allergy

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