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Diagnostic Task Specific Activations in Functionoal Mri and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis
Stoyanov, D.; Aryutova, K.; Kandilarova, S.; Paunova, R.; Arabadzhiev, Z.; Todeva-Radneva, A.; Kostianev, S.; Borgwardt, S. Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis. Diagnostics2021, 11, 95.
Stoyanov, D.; Aryutova, K.; Kandilarova, S.; Paunova, R.; Arabadzhiev, Z.; Todeva-Radneva, A.; Kostianev, S.; Borgwardt, S. Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis. Diagnostics 2021, 11, 95.
Stoyanov, D.; Aryutova, K.; Kandilarova, S.; Paunova, R.; Arabadzhiev, Z.; Todeva-Radneva, A.; Kostianev, S.; Borgwardt, S. Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis. Diagnostics2021, 11, 95.
Stoyanov, D.; Aryutova, K.; Kandilarova, S.; Paunova, R.; Arabadzhiev, Z.; Todeva-Radneva, A.; Kostianev, S.; Borgwardt, S. Diagnostic Task Specific Activations in Functional MRI and Aberrant Connectivity of Insula with Middle Frontal Gyrus Can Inform the Differential Diagnosis of Psychosis. Diagnostics 2021, 11, 95.
Abstract
We constructed a novel design integrating the administration of a clinical self-assessment scale with simultaneous acquisition of functional Magnetic Resonance Imaging (fMRI), aiming at cross-validation between psychopathology evaluation and neuroimaging techniques. We hypothesized that areas demonstrating differential activation in two groups of patients (paranoid and depressive) will have distinct connectivity patterns and structural differences.
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