Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Synthesis, Structural Characterization, and Biological Activities of Organically Templated Cobalt Phosphite (C4N2H14)[Co(H2PO3)4]·2H2O

Najlaa Hamdi
,
Souad Chaouch
,
Ivan da Silva
ORCID logo ,
Mohamed Ezahri
,
Mohammed Lachkar
ORCID logo ,
Rama Alhasan
ORCID logo ,
Ahmad Yaman Abdin
ORCID logo ,
Claus Jacob
ORCID logo ,
Brahim El Bali
Version 1 : Received: 17 January 2019 / Approved: 5 March 2019 / Online: 12 March 2019 (00:00:00 CET)
Version 2 : Received: 17 January 2019 / Approved: 5 March 2019 / Online: 25 July 2019 (00:00:00 CEST)
Version 3 : Received: 12 March 2019 / Approved: 24 January 2019 / Online: 15 November 2019 (00:00:00 CET)
Version 4 : Received: 16 November 2021 / Approved: 22 November 2021 / Online: 22 November 2021 (08:43:49 CET)

A peer-reviewed article of this Preprint also exists.

Hamdi, N.; Chaouch, S.; da Silva, I.; Ezahri, M.; Lachkar, M.; Alhasan, R.; Abdin, A.Y.; Jacob, C.; Bali, B.E. Synthesis, Structural Characterization, and Biological Activities of Organically Templated Cobalt Phosphite (H2DAB)[Co(H2PO3)4]·2H2O. Sci 2022, 4, 5. Hamdi, N.; Chaouch, S.; da Silva, I.; Ezahri, M.; Lachkar, M.; Alhasan, R.; Abdin, A.Y.; Jacob, C.; Bali, B.E. Synthesis, Structural Characterization, and Biological Activities of Organically Templated Cobalt Phosphite (H2DAB)[Co(H2PO3)4]·2H2O. Sci 2022, 4, 5.

Abstract

A novel hybrid phosphite (C4N2H14)[Co(H2PO3)4]·2H2O was synthesized with 1,4- diaminobutane (dabn) as a structure-directing agent using slow evaporation method. Single crystal X-ray diffraction analysis showed that it crystallizes in the P\-1 triclinic space group, with the following unit cell parameters (Å, °) a = 5.4814 (3), b = 7.5515 (4), c = 10.8548 (6), α = 88.001 (4), β = 88.707 (5), γ = 85.126 (5), and V = 447.33 (4) Å3. The crystal structure was built up from corner-sharing [CoO6]-octahedrons, forming chains parallel to [001], which are interconnected by H2PO3− pseudo-tetrahedral units. The diprotonated 1,4-butanediammonium molecules, residing between the parallel chains, interacted with the inorganic moiety via hydrogen bonds leading thus to the formation of the 3D crystal structure. The Fourier transform infrared spectrum showed characteristic bands corresponding to the phosphite group and the organic molecule. The thermal decomposition of the compound consisted mainly of the loss of the organic moiety and the water molecules. The biological tests exhibited significant activity against Candida albicans and Escherichia coli strains in all used concentrations, while less activity was pronounced when tested against Staphylococcus epidermidis and Saccharomyces cerevisiae, while there was no activity against the nematode model Steinernema feltiae.

Keywords

hybrid phosphite; X-rays crystal structure; FTIR; thermal behavior; biological activities; antimicrobial; micro-organisms

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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